Bong Jin Ko; Eun Jin Kim; Dae Seop Lim; Jang Won Park; Jae Woong Tae; Ji Yeon Ryu; Suk Hoon Choi

doi:10.3947/ic.2010.42.6.424

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Ko, Kim, Lim, Park, Tae, Ryu, and Choi: A Case of Guillain-Barré Syndrome Following Plasmodium vivax infection

Case Report

Infection & Chemotherapy

Infection & Chemotherapy 2010; 42(6): 424-427.

Published online: 31 December 2010

DOI: https://doi.org/10.3947/ic.2010.42.6.424

A Case of Guillain-Barré Syndrome Following Plasmodium vivax infection

Bong Jin Ko¹, Eun Jin Kim², Dae Seop Lim¹, Jang Won Park¹, Jae Woong Tae¹, Ji Yeon Ryu³, Suk Hoon Choi¹

¹Department of Internal Medicine, Hanil General Hospital, Seoul, Korea.

²Department of Pediatrics, Hanil General Hospital, Seoul, Korea.

³Department of Neurology, Hanil General Hospital, Seoul, Korea.

Correspondence to Suk Hoon Choi, M.D. Department of Internal Medicine, Hanil General Hospital, Ssangmun3-dong, Dobong-gu, Seoul 132-703, Korea. Tel: +82-2-901-3018, Fax: +82-2-901-3613, Esteprimavera@hanmail.net

Received 30 June 2010 Revised 30 August 2010 Accepted 31 August 2010

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

A 28-year-old male was admitted to our medical center with general myalgia and fever. After a series of tests, he was diagnosed with P. vivax malaria. On the 5th hospital day, the patient complained of tingling sensation on both hands and feet, which acutely progressed to ascending symmetric motor paralysis. Nerve conduction velocity test and cerebrospinal fluid analysis showed albumino-cytologic dissociation, suggesting polyradiculopathy, and thus he was diagnosed with Guillain-Barré syndrome. After 5-day treatment with intravenous immunoglobulin, and antificial ventilator therapy the patient fully recovered. In the literature, only 22 cases of Guillain-Barré syndrome associated with Plasmodium have been reported; 19 cases were caused by Plasmodium falciparum and 3 were by P. vivax. Herein, we report the first case of Guillain-Barré Syndrome associated with P. vivax malaria in Korea.

Keywords: Guillain-Barré syndrome, Plasmodium vivax, Malaria

Figures and Tables

Figure 1

Result of motor nerve conduction velocity. Right median nerve shows delayed latency (12.4 ms), low amplitude (0.1 mV), and slow velocity (37 m/sec). Left tibial nerve shows delayed latency (0.1 ms), low amplitude (0.9 mV), and slow velocity (28 m/sec).

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