A Case of Endocarditis due to Granulicatella adiacens

Mi Ryoung Seo; Yoon Soo Park; Eui Joo Kim; Heon Nam Lee; Kyong Yong Oh; Yiel-Hae Seo; Chang Hyu Choi

doi:10.3947/ic.2010.42.5.311

Journal List > Infect Chemother > v.42(5) > 1035034

Go to TopGo to Top Go to BottomGo to Bottom

TOOLS

Seo, Park, Kim, Lee, Oh, Seo, and Choi: A Case of Endocarditis due to Granulicatella adiacens

Case Report

Infection & Chemotherapy

Infection & Chemotherapy 2010; 42(5): 311-314.

Published online: 31 October 2010

DOI: https://doi.org/10.3947/ic.2010.42.5.311

A Case of Endocarditis due to Granulicatella adiacens

Mi Ryoung Seo¹, Yoon Soo Park¹, Eui Joo Kim¹, Heon Nam Lee¹, Kyong Yong Oh¹, Yiel-Hae Seo², Chang Hyu Choi³

¹Department of Internal Medicine, Gachon University of Medicine and Science, Incheon, Korea.

²Department of Laboratory Medicine, Gachon University of Medicine and Science, Incheon, Korea.

³Department of Thoracic and Cardiovascular Surgery, Gachon University of Medicine and Science, Incheon, Korea.

Correspondence to Chang Hyu Choi, M.D. Department of Thoracic and Cardiovascular Surgery, Gil Medical Center, Gachon University of Medicine and Science, 1198 Guwol-dong, Namdong-gu, Incheon 405-760, Korea. Tel: +82-32-460-8311, Fax: +82-32-460-3668, cch624@gilhospital.com

Received 27 April 2010 Revised 18 August 2010 Accepted 13 September 2010

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Granulicatella species are nutritionally variant streptococci first described in 1961. Granulicatella species form a part of the normal flora of the oral cavity, genitourinary tract, and intestinal tract. These micro-organisms cause bacteremia or local infections such as endocarditis, central nervous system infections, arthritis, and osteomyelitis. Since isolation of Granulicatella species is difficult, only a few cases of infection caused by this microorganism have been reported. Herein, we report a case of endocarditis caused by Granulicatella adiacens in a 46-year-old patient with ventricular septal defect.

Keywords: Granulicatella adiacens, Endocarditis, Nutritionally variant streptococci

Figures and Tables

Figure 1

Intraoperative finding. Subarterial type VSD is located under the PV. Chronic healed vegetation tissue is seen on the PV.

PV, Pulmonic valve.

References

1. Collins MD, Lawson PA. The genus Abiotrophia(Kawamura et al.) is not monophyletic: proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov.,Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov. Int J Syst Evol Microbiol. 2000. 50:365–369.

2. Rosenthal O, Woywodt A, Kirschner P, Haller H. Vertebral osteomyelitis and endocarditis of a pacemaker lead due to Granulicatella (Abiotrophia) adiacens. Infection. 2002. 30:317–319.

3. Hepburn MJ, Fraser SL, Rennie TA, Singleton CM, Delgado B Jr. Septic arthritis caused by Granulicatella adiacens: Diagnosis by inoculation of synovial fluid into blood culture bottles. Rheumatol Int. 2003. 23:255–257.

4. Cerceo E, Christie JD, Nachamkin I, Lautenbach E. Central nervous system infections due to Abiotrophia and Granulicatella species: an emerging challenge? Diagn Microbiol Infect Dis. 2004. 48:161–165.

5. Riede U, Graber P, Ochsner PE. Granulicatella (Abiotrophia) adiacens infection associated with a total knee arthroplasty. Scand J Infect Dis. 2004. 36:761–764.

6. Chang SH, Lee CC, Chen SY, Chen IC, Hsieh MR, Chen SC. Infectious intracranial aneurysms caused by Granulicatella adiacens. Diagn Microbiol Infect Dis. 2008. 60:201–204.

7. Altay M, Akay H, Yildiz E, Duranay M. A novel agent of peritoneal dialysis-related peritonitis: Granulicatella adiacens. Perit Dial Int. 2008. 28:96–97.

8. del Pozo JL, Garcia-Quetglas E, Hernaez S, Serrera A, Alonso M, Pina L, Leiva J, Azanza JR. Granulicatella adiacens breast implant-associated infection. Diagn Microbiol Infect Dis. 2008. 61:58–60.

9. Lee SY, Pai CH. Two cases of nutritionally variant streptococci from patients with endocarditis. Korean J Clin Pathol. 1995. 15:273–280.

10. Kwon O, Park SD, Uh Y, Yoon KJ, Kwon SO, Kim HY. A case of septicemia by Granulicatella adiacens. Infect Chemother. 2005. 37:368–371.

11. Shin KS, Son BR, Jeong HW. A case of Granulicatella adiacens septicemia identified by 16S rRNA sequencing analysis. Korean J Clin Microbiol. 2008. 11:63–65.

12. Frenkel A, Hirsch W. Spontaneous development of L forms of streptococci requiring secretions of other bacteria or sulphydryl compounds for normal growth. Nature. 1961. 191:728–730.

13. Kawamura Y, Hou XG, Sultana F, Liu S, Yamamoto H, Ezaki T. Transfer of Streptococcus adjacens and Streptococcus defectivus to Abiotrophia gen. nov. as Abiotrophia adiacens comb. nov. and Abiotrophia defective comb. nov., respectively. Int J Syst Bacteriol. 1995. 45:798–803.

14. Brouqui P, Raoult D. Endocarditis due to rare and fastidious bacteria. Clin Microbiol Rev. 2001. 14:177–207.

15. Stein DS, Nelson KE. Endocarditis due to nutritionally deficient streptococci: therapeutic dilemma. Rev Infect Dis. 1987. 9:908–916.

16. Lin CH, Hsu RB. Infective endocarditis caused by nutritionally variant streptococci. Am J Med Sci. 2007. 334:235–239.

17. Jeng A, Chen J, Katsivas T. Prosthetic valve endocarditis from Granulicatella adiacens (nutritionally variant streptococci). J Infect. 2005. 51:e125–e129.

18. Perkins A, Osorio S, Serrano M, del Ray MC, Sarriá C, Domingo D, López-Brea M. A case of endocarditis due to Granulicatella adiacens. Clin Microbiol Infect. 2003. 9:576–577.

19. Wilson W, Taubert KA, Gewitz M, Lockhart PB, Baddour LM, Levison M, Bolger A, Cabell CH, Takahashi M, Baltimore RS, Newburger JW, Strom BL, Tani LY, Gerber M, Bonow RO, Pallasch T, Shulman ST, Rowley AH, Burns JC, Ferrieri P, Gardner T, Goff D, Durack DT. American Heart Association. Prevention of infective endocarditis: guidelines from the American Heart Association: a guideline from the American Heart Association Rheumatic Fever, Endocarditis and Kawasaki Disease Committee, Council on Cardiovascular Disease in the Young, and the Council on Clinical Cardiology, Council on Cardiovascular Surgery and Anesthesia, and the Quality of Care and Outcomes Research Interdisciplinary Working Group. J Am Dent Assoc. 2008. 139:Suppl. 3S–24S.

20. Soufflet V, Van de Bruaene A, Troost E, Gewillig M, Moons P, Post MC, Budts W. Behavior of unrepaired perimembranous ventricular septal defect in young adults. Am J Cardiol. 2010. 105:404–407.

TOOLS

Similar articles