A Case of Citrobacter braakii Sepsis Complicated with Hepatocellular Carcinoma

Hae Mi Lee; Sung Ha Bae; Su Nam Lee; Jung Woo Lee; Ah Young Shin; Si Young Yu; Soo-Yeon Lee; Moon Hee Youn; Sun-Young Han; Nam Ik Han; Young Sok Lee; Jin-Hong Yoo

doi:10.3947/ic.2010.42.3.190

Journal List > Infect Chemother > v.42(3) > 1035008

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Lee, Bae, Lee, Lee, Shin, Yu, Lee, Youn, Han, Han, Lee, and Yoo: A Case of Citrobacter braakii Sepsis Complicated with Hepatocellular Carcinoma

Case Report

Infection & Chemotherapy

Infection & Chemotherapy 2010; 42(3): 190-193.

Published online: 30 June 2010

DOI: https://doi.org/10.3947/ic.2010.42.3.190

A Case of Citrobacter braakii Sepsis Complicated with Hepatocellular Carcinoma

Hae Mi Lee, Sung Ha Bae, Su Nam Lee, Jung Woo Lee, Ah Young Shin, Si Young Yu, Soo-Yeon Lee, Moon Hee Youn, Sun-Young Han, Nam Ik Han, Young Sok Lee, Jin-Hong Yoo

Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Corresponding author: Jin-Hong Yoo, M.D. Department of Internal Medicine, Division of Infectious diseases, Bucheon St. Mary's Hospital, 2 Sosa-Dong, Wonmi-Gu, Bucheon-city, Gyunggi-Do, Republic of Korea. Tel: +82-1577-0675, Fax: +82-32-340-2669, jhyoo@catholic.ac.kr

Revised 8 October 2009 Received 11 March 2010 Accepted 13 March 2010

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Citrobacter species is a gram-negative bacilli that can cause opportunistic infections in immunocompromised hosts. Citrobacter braakii refers to the genomospecies 6 of the Citrobacter freundii complex. There are no detailed studies on infections caused by this newly identified specific genetic species in Korea. We herein report a case of a patient with hepatocellular carcinoma who, after undergoing transcatheter arterial chemoembolization, developed biloma which later progressed to C.braakii sepsis and did not respond to treatment. To our knowledge, this is the first reported case in Korea on C. braakii infection resulting in septic shock in a patient with malignancy in Korea.

Keywords: Citrobacter braakii, Biloma, Sepsis

Figures and Tables

Figure 1

Abdomen CT scan shows viable tumor around previous lipiodolized mass in the right hepatic lobe. A 6×4 cm-sized biloma (arrow) is noted around the hepatoduodenal ligament, suggesting bile duct necrosis with perforation.

Figure 2

Newly developed 3.5 cm-sized abscess (arrow head) is observed in the right hepatic lobe on follow-up abdominal CT scan. The biloma around the hepatoduodenal ligament has decreased in size.

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