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Jung Hyun Kim, Soon Hyo Kwon, Eun Jung Lee, Eun Jung Kim, Tae Hyong Kim
, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han
, Jin Seok Jeon, Hyunjin Noh, Dong Cheol Han
Abstract
Since pandemic influenza was declared by WHO at June 2009, severe pandemic influenza cases were reported among pregnant, obese, immunocompromised patients including transplant candidates and recipients were reported. Here we report two cases of pandemic influenza (H1N1 2009) with respiratory distress syndrome in adult patients with kidney transplantation. They were successfully treated with combination of antiviral therapy including high dose oseltamivir. Although clinical symptoms and signs were improved immediately when anti-viral therapy was started, radiologic finding resolved after several weeks.
Figures and Tables
Figure 1
This figure shows the clinical course of the case 1. On day 5 of admission, high body temperature, worsening hypoxia, and dyspnea developed. He was given invasive ventilator care in ICU. Clinical symptoms and signs improved immediately when anti-viral therapy started. ICU, intensive care unit; GW. General ward.
Figure 2
This figure shows the clinical course of the case 2. She was transferred to the ICU because clinical condition deteriorated on day 6 of admission. On day 11 of admission, worsening hypoxia developed, the use of mechanical ventilator care required. Although BK amputation was done, her clinical status continued to deteriorated, with persistent fever and hypoxia. Pandemic influenza (H1N1 2009) was identified by real time PCR from nasal swab on operation day. Clinical symptoms and signs were resolved when anti-viral therapy was started. ICU, intensive care unit; GW. General ward; BK, below-knee.
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