Journal List > J Korean Acad Prosthodont > v.55(3) > 1034932

Labriaga, Hong, Park, Shin, and Lee: A 5-year prospective clinical study of Neobiotech implants for partially edentulous patients



The aim of the present prospective clinical study was to assess the cumulative survival rate (CSR) of Neobiotech implants restored with fixed partial prosthesis in relation to its potential risk factors.

Materials and methods

Thirty six partially edentulous patients received Neobiotech implants and implant supported fixed partial prosthesis at Korea University Guro Hospital Dental Center from November 2009 until November 2011. The observation period was set from the implant placement and the last clinical visit until December 2015. Implant survival rate was determined using the Kaplan-Meier method. The relationship between implant survival rate and the potential risk factors were analysed using the multi Cox proportional analysis (P<.05).


A total of 69 implants were placed in 36 patients after a mean observation period of 45.9 months. Two out of 69 implants failed before loading, yielding a 5-year cumulative survival rate of 97.1%. The maxillary implants have a lesser CSR than the mandibular implants based on log rank test analysis (maxilla=91.3%; mandible=100% P<.05). However, the multi Cox proportional analysis showed that implant location has no significant correlation with implant failure (P>.05).


Neobiotech implants showed predictable results with a 5 year cumulative survival rate of 97.1%. (J Korean Acad Prosthodont 2017;55:272-8)


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Fig. 1.
Measurement of marginal bone level.
Fig. 2.
5-year cumulative survival rate (CSR) of Neobiotech implants by Kaplan-Meir method.
Fig. 3.
Mean marginal bone level from the reference point.
Table 1.
Distribution of i mplants and cumulative survival rate in re elation to investigated risk factors
Risk factors Characteristics Number of implant CSR % P value
Age Younger (< 65) 47 95.7 .331
Advanced (≥ 65) 22 100
Gender Male 26 92.3 .066
Female 43 100
Systemic condition Healthy 47 97.9 .588
Chronic disease 22 95.5
Width Small 8 100 .552
Regular 18 100
Wide 43 95.3
Length Short 11 100 .542
Long 58 96.5
Implant arch location Maxilla 23 91.3 .047∗
Mandible 46 100
Tooth position Ant 8 100 .602
Post 61 96.6
Other Surgery No 50 98.0 .441
Yes 19 94.7
Splinting Splint 26 100 -
Non-splint 41 100
Abutment Ready made 32 100 -
Customized 35 100

Systemic disease included diabetes mellitus and/or cardiovascular disease; Other surgery includes guided bone regeneration (GBR) and/or sinus augmentation; ∗significant difference (log-rank test, P < .05).

Table 2.
Multivariate associations with cumulative survival rate of implants
  B P value Exp (B) Exp (B) 95.0% CI
Lower Upper
Implant arch location (Maxilla vs Mandible) 5.371 .427 215.110 .000 123185820.51
Gender (Male vs Female) 5.041 .423 154.601 .001 35065013.208

Only the risk factors that showed a statistically borderline significant in the log-rank test (P < .20) were included in the multivariate model.

The included risk factors showed no significant correlation with implant failure (P > .05).

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