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Abstract
Background
As the necessity of adult living donor liver transplantation continues to increase, morbidity and mortality of donors has been considered vital. Thus, we performed a sequential analysis of our surgical experience in order to find ways to improve surgical outcomes in right liver donors.
Methods
We performed a retrospective sequential analysis of surgical outcomes of consecutive 245 right liver donors by 50 cases between October 2002 and November 2012.
Results
Hospital stay (13.78 to 10.98 days), operation time (432.76 to 389.98 minutes), amount of intra operative bleeding (577.70 to 502.56 mL), and perioperative transfusion rates decreased from the initial 50 cases to the last 45 cases. A total of 96 grade I complications by Clavien-Dindo classification decreased from 26 to 17. Ten and three cases had grade IIIa and IIIb complications, respectively. There were three cases of wound infection, two cases of duodenal ulcer bleeding, one case of pleural effusion, and four cases of bile leakage of grade IIIa complications, and one case of postoperative intestinal obstruction, one case of generalized peritonitis by small bowel perforation, and one case of bile leakage of grade IIIb complications. There was no mortality during the follow-up period.
References
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Table 1.
Patient’ s characteristics
Table 2.
Surgical outcomes and complications of right liver donors by sequential 50 cases
| Case | Group I (1st∼50th) | Group II (51st∼100th) | Group III (101st∼150th) | Group IV (151st∼200th) | Group V (201st∼245th) | Total No. | P value |
|---|---|---|---|---|---|---|---|
| Hospital stay (day) | 13.78±5.21 | 14.78±4.31 | 12.86±4.17 | 11.36±10.98 | 10.98±2.17 | ＜0.001 | |
| Operation time (min) | 432.76±82.70 | 451.72±66.19 | 414.36±52.73 | 383.08±47.56 | 389.98±67.50 | ＜0.001 | |
| Bleeding (mL) | 557.50±392.21 | 436.80±422.32 | 475.70±310.88 | 403.61±221.15 | 402.56±199.43 | NS | |
| Transfusion of pRBC (unit) | 4 | 2 | 3 | 0 | 0 | NS | |
| Complications a | |||||||
| I | 26 | 21 | 17 | 15 | 17 | 96 | NS |
| II | 0 | 1 | 1 | 2 | 0 | 4 | NS |
| IIIa | 2 | 3 | 2 | 1 | 2 | 10 | NS |
| IIIb | 0 | 1 | 0 | 2 | 0 | 3 | NS |
| Abbreviations: pRBC, packed red blood cell; NS, statistically not significant. | |||||||
Table 3.
Descriptions of postoperative complications
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