Journal List > J Korean Soc Transplant > v.25(1) > 1034360

J Korean Soc Transplant. 2011 Mar;25(1):8-14. Korean.
Published online March 31, 2011.  https://doi.org/10.4285/jkstn.2011.25.1.8
Copyright © 2011 The Korean Society for Transplantation
Management of Posttransplantation Diabetes Mellitus (PTDM)
Bong Soo Cha, M.D., and Jae Hoon Moon, M.D.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.

Corresponding author (Email: bscha@yuhs.ac )
Received February 28, 2011; Accepted March 03, 2011.

Abstract

New-onset diabetes after transplantation (NODAT) is a common complication of solid-organ transplantation. As long-term posttransplant survival continues to improve, increasing attention has been placed on NODAT. Because NODAT is a potent predictor of graft failure and cardiovascular mortality in the transplant population, early detection and management of NODAT are important issues. The risk factors for NODAT in transplant recipients include older age, obesity, family history, hepatitis C virus infection, and immunosuppressive agents, such as corticosteroids and calcineurin inhibitors. Management of NODAT must be considered at the pretransplantation stage to screen high risk patients and prevent NODAT. Although NODAT management is similar to type 2 diabetes management in the general population, there are some specific considerations in NODAT management, including the immunosuppressive agent. Further studies are needed to suggest optimal management guidelines for NODAT.

Keywords: Diabetes mellitus; Organ transplantation; Risk factors; Postoperative complications; Diagnosis; Treatment outcome

Tables


Table 1
Treatment guideline for type 2 diabetes patients
Click for larger image

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