Journal List > J Korean Soc Transplant > v.25(3) > 1034341

J Korean Soc Transplant. 2011 Sep;25(3):165-168. Korean.
Published online September 30, 2011.
Copyright © 2011 The Korean Society for Transplantation
Issues on Long-term Management after Liver Transplantation in Children
Kyung Mo Kim, M.D.
Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Asan Medical Center Children's Hospital, University of Ulsan College of Medicine, Seoul, Korea.

Corresponding author (Email: )
Received September 02, 2011; Accepted September 05, 2011.


With advancements of liver transplantation, the patient's survival improved remarkably. Thus the long-term survivors are increasing especially for the pediatric liver transplantation recipients. Consequently they are facing the challenge of maintaining graft function while minimizing long-term complications. In this review, I will discuss calcineurin inhibitor toxicity, problems with steroid, adherence to medical regimen, posttransplant growth, chronic graft dysfunction, tolerance.

Keywords: Child; Liver transplantation; Postoperative complications; Medication adherence; Transplantation tolerance


Fig. 1
The overall rates of patient survival at two time period. Those before 2003 at 1 and 5 years were 86.4%, 79.5%, and 78.4%, respectively. Those after 2003 were 95.4% and 95.4%, respectively (P<0.05, Kaplan-Meier method). There is a statistically significant improvement in patient survival. Reprinted from reference [2].
Click for larger image

Fig. 2
Post-transplantation height mean standard deviation scores (zH) of children with retarded growth (•) and normal growth (▪) at time of transplantation. The height of growth-retarded children was restored by catch-up growth and nongrowth- retarded children grew adequately for up to 7 years. Adapted from reference [13].
Click for larger image

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