Journal List > J Korean Soc Transplant > v.25(3) > 1034339

J Korean Soc Transplant. 2011 Sep;25(3):151-154. Korean.
Published online September 30, 2011.
Copyright © 2011 The Korean Society for Transplantation
Indication of Pediatric Liver Transplantation
Mi Jin Kim, M.D. and Yon Ho Choe, Ph.D.
Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Corresponding author (Email: )
Received July 14, 2011; Accepted July 21, 2011.


Pediatric liver transplantation is a well-established and successful strategy. Survival after liver transplantation has improved significantly over the last decade with pediatric recipients. Biliary atresia is the most common indication of pediatric liver transplantation and needs adequate selection of patients and timing of transplantation in order to achieve best results. In fulminant hepatic failure, laboratory data and neurological signs help decide the need for transplantation and determine the prognosis. A judicious communication between physicians and parents is important for deciding appropriate time of liver transplantation.

Keywords: Liver transplantation; Children; Indication


Table 1
Indications for liver transplantation at Children's Hospital of Pittsburgh from 1981 to 1998
Click for larger image

Table 2
Underlying causes of 144 liver transplantation at Samsung Medical Center from 1996 to 2010
Click for larger image

Table 3
Indications for liver transplantation at Asan Medical Center from 1994 to 2006
Click for larger image

Table 4
The study of Fulminant hepatic failure at Samsung Medical Center from 1996 to 2010
Click for larger image

1. Starzl TE, Marchioro TL, Vonkaulla KN, Hermann G, Brittain RS, Waddell WR. Homotransplantation of the liver in humans. Surg Gynecol Obstet 1963;117:659–676.
2. Kim ST, Park YH, Lee KU, Yoon YK, Kim SW, Yang HK, et al. An experience of liver transplantation in Korea. J Korean Soc Transplant 1988;2:27–36.
3. Lee SG, Lee YJ, Kwon TW, Kim KM, Choi KM, Park KM, et al. Liver transplantation from a living donor to his daughter. J Korean Soc Transplant 1995;9:187–192.
4. Jain A, Mazariegos G, Kashyap R, Kosmach-Park B, Starzl TE, Fung J, et al. Pediatric liver transplantation. A single center experience spanning 20 years. Transplantation 2002;73:941–947.
5. Oh SH, Kim KM, Kim DY, Lee YJ, Rhee KW, Jang JY, et al. Long-term outcomes of pediatric living donor liver transplantation at a single institution. Pediatr Transplant 2010;14:870–878.
6. Goss JA, Shackleton CR, Swenson K, Satou NL, Nuesse BJ, Imagawa DK, et al. Orthotopic liver transplantation for congenital biliary atresia. An 11-year, single-center experience. Ann Surg 1996;224:276–284.
discussion 284-7.
7. Trey C, Davidson CS. The management of fulminant hepatic failure. Prog Liver Dis 1970;3:282–298.
8. Bernuau J, Rueff B, Benhamou JP. Fulminant and subfulminant liver failure: definitions and causes. Semin Liver Dis 1986;6:97–106.
9. Squires RH Jr, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, et al. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr 2006;148:652–658.
10. Sternlieb I. Wilson's disease: indications for liver transplants. Hepatology 1984;4 1 Suppl:15S–17S.
11. Kuang AA, Rosenthal P, Roberts JP, Renz JF, Stock P, Ascher NL, et al. Decreased mortality from technical failure improves results in pediatric liver transplantation. Arch Surg 1996;131:887–892.
discussion 892-3.
12. McDiarmid SV, Merion RM, Dykstra DM, Harper AM. Selection of pediatric candidates under the PELD system. Liver Transpl 2004;10 10 Suppl 2:S23–S30.
13. Shinkai M, Ohhama Y, Take H, Fukuzato Y, Fujita S, Nishi T. Evaluation of the PELD risk score as a severity index of biliary atresia. J Pediatr Surg 2003;38:1001–1004.
Similar articles

Pediatric Liver Transplantation

Pediatric liver transplantation in Korea: long-term outcomes and allocations

Pediatric liver transplantation in Korea: long-term outcomes and allocations

Anesthetic Management in Pediatric Liver Transplantation

Indication and Prognosis of Liver Transplantation