Innate Lymphoid Cells and Infection

Chang-Hwa Song

doi:10.4167/jbv.2017.47.2.105

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Song: Innate Lymphoid Cells and Infection

Research Update (Minireview)

Journal of Bacteriology and Virology 2017; 47(2): 105-109.

Published online: 25 June 2017

DOI: https://doi.org/10.4167/jbv.2017.47.2.105

Innate Lymphoid Cells and Infection

Chang-Hwa Song^1,²

¹Department of Microbiology, College of Medicine, Chungnam National University, Daejeon, Korea.

²Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, Korea.

Corresponding author: Dr. Chang-Hwa Song. Department of Microbiology, College of Medicine, Chungnam National University, 266 Munhwa-ro, Jung-gu, Daejeon 35015, Korea. Phone: +82-42-580-8245, Fax: +82-0504-067-5722, songch@cnu.ac.kr

Received 18 April 2017 Revised 20 April 2017 Accepted 24 April 2017

(open-access):

This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).

Abstract

The functions of innate lymphoid cells (ILCs) have been known to play an important role in immunity and immune responses. ILCs are rapidly-responding cells that are involved in tissue remodeling, cancer, the regulation of autoimmune inflammation and resistance to pathogens. Understanding the role of ILCs in regulating immune response could be useful for the development of new therapeutic strategies against emerging or re-emerging infectious diseases. However, the relevance of ILCs in infectious diseases was not fully uncovered. This review provides an overview of the current knowledge of the functional characteristics of ILCs and how these cells interact with pathogens to mediate immune responses.

Keywords: Infections, Innate lymphoid cells, Innate immunity

Notes

This study was supported by research fund of Chungnam National University.

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