Prevalence of Hepatitis B Virus and HIV Co-infection in Korea

Hyun-Ho Lee; Hae-Guen Hong; Jong-Seong Son; Sun-Mok Kwon; Bu-Geon Lim; Kang-Bum Lee; Gu-Hwan Kim

doi:10.4167/jbv.2016.46.4.283

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Lee, Hong, Son, Kwon, Lim, Lee, and Kim: Prevalence of Hepatitis B Virus and HIV Co-infection in Korea

Communication

J Bacteriol Virol 2016;46(4):283-287.

Published online: 9 February 2016

DOI: https://doi.org/10.4167/jbv.2016.46.4.283

Prevalence of Hepatitis B Virus and HIV Co-infection in Korea

Hyun-Ho Lee^∗, Hae-Guen Hong, Jong-Seong Son, Sun-Mok Kwon, Bu-Geon Lim, Kang-Bum Lee, Gu-Hwan Kim

Microbiological Inspection Team, Gyeonggi-do Research Institute of Health & Environment, Uijeongbu, Korea

^∗Corresponding author: Hyun-Ho Lee. Microbiological Inspection Team, Gyeonggi-do Research Institute of Health & Environment, Uijeongbu, 16205, Korea. Phone: +82-31-8030-5925, Fax: +82-31-8030-5929, e-mail: nicechap1@gg.go.kr

Received 24 July 201613 October 2016 Accepted 24 October 2016

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) have a common route like sexually transmitted infections (STIs), vertical transmission and blood transfusion, etc. Therefore, it was necessary to be an attempt to confirm the relationship of HBV and HIV in Korea. We investigated the prevalence of Hepatitis B surface antigen (HBsAg) and Hepatitis B core antibody (anti-HBc) in HIV positive groups (n=430) and HIV negative groups (n=434) from January 2014 to October 2015. When comparing the prevalence of anti-HBc between the two groups, HIV positive group (36.0%) showed a higher prevalence than HIV negative group (24.7%), the result was statistically significant (p < 0.05). However, there was a little difference on HBsAg and not significant. Therefore, by showing a clear difference in anti-HBc between the two groups of HIV in Korea, it was confirmed to be associated with co-infections between Hepatitis B and HIV.

Keywords: Hepatitis B, HIV, HBsAg, Anti-HBc

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Figure 1.

Prevalence of HBsAg and anti-HBc according to HIV groups.

Figure 2.

Prevalence of the combination of HBsAg and anti-HBc according to HIV groups.

Table 1.

Prevalence of HBsAg according to periods (modified from ref. 17)

Year	Prevalence (%)
1979. 3 ~ 1981. 2 (18)	6.6
1982. 4 ~ 1983. 3 (19)	8.6
1984. 2 ~ 1985. 11 (20)	8.3
1995. 1 ~ 1995. 12 (21)	8.3
1995. 7 ~ 1997. 12 (22)	5.7
1996. 1 ~ 1996. 12 (21)	4.8
1997. 1 ~ 1997. 12 (21)	3.4
1998. 1 ~ 1998. 12 (21)	3.4
1999. 1 ~ 1999. 12 (21)	2.6
2014. 1 ~ 2015.11^∗	2.3

^∗ HIV negative group (n=434) were analyzed about HBsAg in this study from 2014 to 2015.

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