The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea

Sang Taek Heo; Jeong Rae Yoo; Keun Hwa Lee; Kwan Soo Ko

doi:10.4167/jbv.2015.45.2.155

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Heo, Yoo, Lee, and Ko: The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea

Communication

J Bacteriol Virol 2015;45(2):155-158.

Published online: 9 February 2015

DOI: https://doi.org/10.4167/jbv.2015.45.2.155

The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea

Sang Taek Heo¹, Jeong Rae Yoo¹, Keun Hwa Lee², Kwan Soo Ko^3,^∗

¹Department of Infectious Disease, Jeju National University School of Medicine, Jeju, Korea

²Department of Microbiology and Immunology, Jeju National University School of Medicine, Jeju, Korea

³Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, Suwon, Korea

^∗Corresponding author: Kwan Soo Ko, Ph.D. Department of Molecular Cell Biology, Sungkyunkwan University School of Medicine, 2066 Seobu-ro, Jangan-gu, Suwon 440-746, Korea. Phone: +82-31-299-6223, Fax: +82-31-299-6229, e-mail: ksko@skku.edu

Received 10 May 201526 May 2015 Accepted 28 May 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

In this study, we report the first clinically identified case of severe fever with thrombocytopenia syndrome (SFTS) in a 73-year old man from Jeju Island, South Korea. Although his initial manifestation suggested tsutsugamushi disease with cutaneous lesion, later the patient presented with symptoms characteristic of SFTS. Despite intensive medical therapies upon the clinical diagnosis of SFTS, patient's condition rapidly deteriorated. SFTS is a fatal disease that requires early diagnosis and appropriate supportive treatment.

Keywords: Severe fever with thrombocytopenia syndrome, South Korea, Jeju Island

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Figure 1.

Amplification of S and L segment of SFTSV. (A) S segment of SFTSV was amplified from the SFTS patient's serum by real-time RT-PCR. 1.2% agarose gel electrophoresis demonstrates the 110-bp corresponding to the S segment (B) and the 100-bp corresponding to the L segment (C) of SFTSV.

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