Neutrophils in Immunity

So-Youn Woo

doi:10.4167/jbv.2012.42.2.172

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Woo: Neutrophils in Immunity

Letter to the Editor

Journal of Bacteriology and Virology

Journal of Bacteriology and Virology 2012; 42(2): 172-176.

Published online: 22 June 2012

DOI: https://doi.org/10.4167/jbv.2012.42.2.172

Neutrophils in Immunity

So-Youn Woo

Department of Microbiology, School of Medicine, Ewha Womans University, Seoul, Korea.

Corresponding author: So-Youn Woo. #207, Department of Microbiology, School of Medicine, Ewha Womans University, Seoul, 158-701, Korea. Phone: +82-2-2650-5737, Fax: +82-2-2653-8891, soyounwoo@ewha.ac.kr

Received 21 May 2012 Revised 25 May 2012 Accepted 29 May 2012

Abstract

Neutrophils are the most abundant white blood cells in the peripheral blood and have long been recognized as the major phagocytes in acute infection by destroying extracellular pathogens. Although research on neutrophils hampered by intractability in the experiments, the newly discovered effector functions of neutrophils includes granular proteins, and cytokines, extracellular traps. With all effector mechanism neutrophils play a critical role in the pathogenesis of acute and chronic infection, autoimmunity and cancer.

Keywords: Inflammation, Antimicrobial, Granule, Neutrophil extracellular trap (NET)

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