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Abstract
Purpose
Cough and wheezing are the most common respiratory symptoms in children. Recently, the cough-holter monitoring has been used to estimate the frequency and intensity of cough and wheezing, objectively. In this study, we aimed to evaluate the validity of cough-holter monitoring for the objective assessment of cough and wheezing in the hospitalized children with respiratory symptoms.
Methods
Cough-holter monitoring was performed in 59 children who suffered from cough and/or wheezing. We obtained the information on the frequency and intensity of cough and wheezing from the parents, a pediatrician, and cough-holter monitoring. Visual Analogue Scale (VAS) scores were taken by parents, and the pediatrician estimated the wheezing score by using a stethoscope. We assessed a relationship between the VAS scores, wheezing score, and cough-holter monitoring data.
Results
The frequencies and intensities of cough correlated positively with the VAS scores (r=0.301, P=0.032; and r=0.540, P=0.001, respectively) and the frequencies and intensities of wheezing also correlated positively with the Wheezing scores. (r=0.335, P=0.011; and r=0.457, P=0.001, respectively) The wheezing intensity did not correlate with the Wheezing score in wheezing children. (r=0.321, P=0.089)
Figures and Tables
Fig. 1
Correlations between Visual Analogue Scale (VAS) scores and cough event counts (CEC) (A) and the highest cough component counts per cough event count (CCC/CEC [H]) (B) in total subjects (n=59).
Fig. 2
Correlations between Visual Analogue Scale (VAS) scores and cough event counts (CEC) (A) and the highest cough component counts per cough event count (CCC/CEC [H]) (B) in wheezing subjects.
Fig. 3
Correlations between Visual Analogue Scale (VAS) scores and cough event counts (CEC) (A) and the highest cough component counts per cough event count (CCC/CEC [H]) (B) in nonwheezing subjects.
Fig. 4
Correlations between wheezing scores and number of segment with wheezing (WZ [TR, N]) (A) and the highest total wheezing% (WZ [TR, H]) (B) in total subjects.
Fig. 5
Correlations between wheezing scores and number of segment with wheezing (WZ [TR, N]) (A) and the highest total wheezing% (WZ [TR, H]) (B) in wheezing subjects.
Table 1
Wheezing and Retraction Scale of the Respiratory Distress Assessment Instrument (Wheezing Score)
Reprinted from Lowell et al. Pediatrics 1987;79:939-4, with permission of American Academy of Pediatrics2).
Table 3
VAS Scores, Wheezing Scores and Cough-Holter Results of the Total Subjects
Values are presendted as mean±standard deviation.
VAS, Visual Analogue Scale; CEC, cough event count; CCC/CEC (A); average cough component count per cough event count; CCC/CEC (H), highest cough component count per cough event count; WZ (TR, N), no. of segment with wheezing (>5%); WZ (TR, A), average total wheezing; WZ (TR, H); highest total wheezing.
Table 4
Subgroup Results of the Cough-holter Tests according to the Presence of Wheezing
Values are presendted as mean±standard deviation.
WZ (+), wheezing children; WZ (-), nonwheezing children; VAS, Visual Analogue Scale; CEC; no. of cough segment, CCC/CEA (A); average cough component count per cough event, CCC/CEC (H); highest cough component count per cough event count, WZ (TR) n; number of segment with wheezing (>5%), WZ (TR, A); average total wheezing; WZ (TR, H), highest total wheezing.
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