Clinical Characteristics of Children with Lobar Pneumonia Caused by Mycoplasma pneumoniae

Eun Ae Yang; Mi Hyeon Gang; Sun Young You; Jin Hwan Kim; Jae Ho Lee

doi:10.7581/pard.2012.22.3.256

Journal List > Pediatr Allergy Respir Dis > v.22(3) > 1033182

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Yang, Gang, You, Kim, and Lee: Clinical Characteristics of Children with Lobar Pneumonia Caused by Mycoplasma pneumoniae

Original Article

Pediatric Allergy and Respiratory Disease

Pediatric Allergy and Respiratory Disease 2012; 22(3): 256-264.

Published online: 30 September 2012

DOI: https://doi.org/10.7581/pard.2012.22.3.256

Clinical Characteristics of Children with Lobar Pneumonia Caused by Mycoplasma pneumoniae

Eun Ae Yang, MD¹, Mi Hyeon Gang¹, Sun Young You, MD¹, Jin Hwan Kim, MD, PhD², Jae Ho Lee, MD, PhD¹

¹Department of Pediatrics, Chungnam National University School of Medicine, Daejeon, Korea.

²Department of Radiology, Chungnam National University School of Medicine, Daejeon, Korea.

Corresponding author (immlee@cnu.ac.kr)

Received 3 April 2012 Revised 16 July 2012 Accepted 16 September 2012

Abstract

Purpose

This study was conducted to evaluate the prevalence, clinical characteristics and laboratory findings of lobar pneumonia in children caused by Mycoplasma pneumonia and to find a diagnostic tool for identifying M. pneumoniae infection in children.

Methods

We analyzed medical records of 78 children between March 2010 and December 2011, who were admitted to our hospital and diagnosed with lobar pneumonia on the basis of chest X-rays. White blood cells (WBC), C-reactive protein (CRP), procalcitonin (PCT), specific antibodies to M. pneuomoniae, and cold agglutinin (CA) were measured at the time of admission. Children were divided into 2 groups: those with M. pneuomoniae infection (group A) and those without infection (group B). Group A children were also subdivided into 2 categories: those with increased CA (group 1) and those without (group 2).

Results

The prevalence of lobar pneumonia was higher in the year 2011 than in 2010. M. pneuomoniae infection usually occurs in summer and autumn. Group A children accounted for 75.6% (59/78) of all the cases. The onset ages was higher in group A than in group B (P=0.016). WBC counts and PCT values were higher in group B than in group A.(P=0.015 and P=0.011, respectively) Radiologic findings showed that the lower lobe was most commonly involved without predilection for either side and pleural effusion was present in 13.6% of all the cases. The duration of fever before admission was longer in group 1 than in group 2.(P=0.019)

Conclusion

It is concluded that lobar pneumonia caused by M. pneuomoniae can be more accurately diagnosed using serum PCT values than using CRP values.

Keywords: Pneumonia, Mycoplasma pneumoniae, Child, Procalcitonin

Figures and Tables

Fig. 1

Monthly distribution of lobar pneumonia.

Table 1

Clinical Chracteristics and Laboratory Data for Mycoplasma pneumoniae (groupA) vs. Non-M. pneumoniae (group B)

Values are presented as mean±SD.

CRP, C-reactive protein; PCT, procalcitonin.

^*Mann-Whitney test. ^†Chi-spuare test. ^‡Fisher's exact test. ^§P<0.05.

Table 2

Involved Area of Lobar Pneumonia Depending on Infection of Mycoplasma pneumoniae

Rt, right; Lt, left; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe; LUL, left upper lobe; LLL, left lower lobe.

Table 3

Clinical Characteristics and Laboratory Data for Groups with Increased Cold Agglutinin (group 1) and without (group 2) in Mycoplasma pneumoniae Pneumonia

Values are presented as mean±SD.

CRP, C-reactive protein; PCT, procalcitonin.

^*Mann-Whitney test. ^†Chi-square test. ^‡Fisher's exact test. ^§P<0.05.

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