Journal List > Korean J Androl > v.29(1) > 1033098

Park, Kim, Choe, Kim, and Park: The Use of Phytotherapy in Male Patients with a Lower Urinary Tract Symptoms Due to Benign Prostatic Hyperplasia: Single Center Study

Abstract

Purpose

Recently, the use of complementary and alternative medicine (CAM) is increasing among patients with low urinary tract symtoms (LUTS) caused by benign prostate hyperplasia (BPH). We assessed current usage and awareness of phytotherapy, the most ubiquitous CAM, in BPH/LUTS patients.

Materials and Methods

A total of 204 patients with BPH who completed a questionnaire between January 2009 and December 2010 were enrolled. The questionnaire was composed of questions about age, education level, accompanying disease, type of phytotherapy, route of purchase, reason of taking medicine and whether the patient is using phytotherapy in combination with conventional medicine.

Results

The mean age was 55.5±8.7 years. 56 of the total patients (27.5%) were using phytotherapy. The patients who were accompanied with erectile dysfunction used phytotherapy the most. The most commonly used phytotherapy for prescription and health functional food was Saw palmetto. The most common route of purchase was by clinician's prescription (46.4%). Most patients answered the dissatisfaction of present treatment's effect as the main reason for using phytotherapy. The number of patients who were taking combination therapy of BPH medication and phytotherapy was much more than using phytotherapy alone.

Conclusions

27.5% of patients who had BPH/LUTS were using phytotherapy. This is the point of time for many urologists to acquire the knowledge of studies and latest research of phytotherapy and use it in treating patients with BPH/LUTS.

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Table 1.
Characteristics of patients
No. of patients (%) Phytotherpay users Phytotherapy nonusers p-value
No. of patients (%) No. of patients (%)
Age 0.125
 20∼39 34 (16.7) 4 (11.8) 30 (88.2)
 40∼49 44 (21.6) 14 (31.8) 30 (68.2)
 50∼59 62 (30.4) 20 (32.3) 42 (67.7)
 60∼69 44 (21.6) 12 (27.3) 32 (72.7)
 ≥70 20 (9.8) 6 (30) 14 (70)
Education 0.052
 ≤Graduated elementary school 48 (23.5) 6 (10.7) 42 (89.3)
 Graduated middle school 40 (19.6) 8 (20) 32 (80)
 Graduated high school 48 (23.5) 16 (33.3) 32 (66.7)
 Graduated college or university 48 (23.5) 18 (37.5) 30 (72.5)
 ≥Graduated graduate school 20 (9.8) 8 (40) 12 (60)
Comorbidities 0.044
 Erectile dysfunction 50 (24.5) 20 (40) 30 (60)
 Diabetes 24 (11.8) 6 (25) 18 (75)
 Hypertension 28 (13.7) 8 (28.6) 20 (71.4)
Table 2.
Types of phytotherapy used by patients
Types No. of cases (%)
Pharmaceuticals
 Saw palmetto 14 (25)
 African plum 6 (10.7)
 Stinging nettle+African plum 4 (7.1)
 Rye pollen 2 (3.6)
Functional foods
 Saw palmetto 22 (39.3)
 Lycopene (tomato) 6 (10.7)
 Pumpkin seed 2 (3.6)
Total 56 (100)
Table 3.
Channels of purchase
No. of cases (%)
Prescription by a physician 26 (46.4)
Newspaper advertisement 10 (17.6)
TV commercial 8 (14.3)
Present 6 (10.7)
Internet 2 (3.6)
Special store 2 (3.6)
Department store, Mart 2 (3.6)
Total 56 (100)
Table 4.
Purpose of phytotherapy use
No. of cases (%)
Dissatisfaction with conventional medicine 20 (35.7)
Less side effects 16 (28.6)
More efficient 10 (17.9)
Inexpensive 10 (17.9)
Total 56 (100)
Table 5.
Percentage of combination treatment
No. of cases (%)
Phytotherapy+medication 44 (78.6)
Phytotherapy only 12 (21.4)
Total 56 (100)
Table 6.
Currently available phytotherapeutic agents for BPH/LUTS in Korea
Common name Scientific name Name and company
Pharmaceuticals
Saw palmetto Serenoa repens Someto 320 mg
(Pharmbio Korea
Co.)
African plum Pygeum Loseta 25 mg
africanum (Theragen etex Co.)
Lostar cap. 25 mg
(Jinyang Pharmacy
Co.)
Masculin cap. 25 mg
(Hansung Pharmacy
Co.)
Prostame soft cap.
(Chunggei Pharmacy
Co.)∗
Stinging nettle Urtica dioica Prostame soft cap.
(Chunggei Pharmacy
Co.)∗
Rye pollen Secale cerale Cernilton tab. (Dongkoo
Pharmacy Co.)
Functional foods
Saw palmetto Serenoa repens
Pumpkin seed
Tomato
lycopene

Complex BPH/LUTS: benign prostatic hyperplasia/lower urinary tract symptoms.

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