A Case of Deep Vein Thrombosis Following Iron Deficiency Anemia in Cerebral Palsy

Ji Eun Park; Yoon Jeong Cho; Seon A An; Hui Seung Hwang; Soo Young Lee; Seung Yeon Chung; Dae Chul Jeong

doi:10.5045/kjh.2009.44.4.336

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Park, Cho, An, Hwang, Lee, Chung, and Jeong: A Case of Deep Vein Thrombosis Following Iron Deficiency Anemia in Cerebral Palsy

Case Report

Korean J Hematol 2009;44(4):336-340.

Published online: 20 December 2009

DOI: https://doi.org/10.5045/kjh.2009.44.4.336

A Case of Deep Vein Thrombosis Following Iron Deficiency Anemia in Cerebral Palsy

Ji Eun Park, M.D., Yoon Jeong Cho, M.D., Seon A An, M.D., Hui Seung Hwang, M.D., Soo Young Lee, M.D., Seung Yeon Chung, M.D., Dae Chul Jeong, M.D.

Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence to：Dae Chul Jeong, M.D. Department of Pediatrics, College of Medicine, The Catholic University of Korea, Incheon St. Mary's Hospital 665, Bupyung-6-dong, Bupyung-gu, Incheon 403-720, Korea Tel: ＋82-32-510-5500, Fax: ＋82-32-503-9724 E-mail: dcjeong@catholic.ac.kr

Received 1 October 2009 Revised 25 October 2009 Accepted 28 October 2009

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Thrombotic complications in iron-deficiency anemia (IDA) are rare. We now report a case of deep vein thrombosis following iron deficiency anemia in cerebral palsy. A 20 year old male was admitted to our hospital? due to a pale appearance. He was diagnosed as having spastic cerebral palsy. On admission, a complete blood cell count showed IDA with thrombocytosis. Prothrombin time and activated partial thromboplastin time were within the normal range. We observed swelling and edema on the left thigh and ankle without tenderness. We performed Doppler sonography and computed tomography. Thrombi were located in the left common iliac vein and left superficial femoral vein with elevated D-dimer levels. We started heparin therapy. We excluded intravascular hemolysis or a hypercoagulable state when we found that Ham's test, anti-cardiolipin antibody, and lupus anticoagulant were negative. The patient died due to hypoxemia and cardiac failure despite ventilator care with anti-coagulant therapy.

Keywords: Iron deficiency anemia, Deep vein thrombosis, Spastic cerebral palsy

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Fig. 1.

Thrombi on the left common iliac vein on Doppler ultrasonography. There were shown heterogenous echogenic density of thrombi (arrow) on left common iliac vein.

Fig. 2.

The distribution of thrombi on venous phase of computerized tomography. There were shown thrombi (arrow) on the left common iliac vein (A) and the left superficial femoral vein (B).

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