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Abstract
Primary extranodal non-Hodgkin's lymphomas comprise approximately 10% of all non-Hodgkin's lymphomas. However, primary tracheal non-Hodgkin's lymphoma is extremely rare, being mainly mucosa-associated lymphoid tissue lymphoma. A 65-year-old female has dry cough for one year. She was diagnosed as diffuse large B-cell lymphoma via bronchoscopic-guided biopsy. She was treated with four cycles of the R-CHOP regimen and adjuvant radiotherapy. After completion of the combined treatment, the treatment response was complete remission, and the disease free survival was 26 months.
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Fig. 1
Serial bronchoscopic findings. (A) At 20cm from upper incisor, multi-lobulated, multi-lobulated tumor with vascularization was seen. the tumor obstructed the tracheal lumen by about 50%. (B, C) Comparing previous bronchoscopic finding. the size of tracheal lymphoma was marked decreased at about 5cm above carina. (B) After the patient received 2 cycles of combination chemotherapy with R-CHOP regimen. (C) After the patient received 4 cycles of combination chemotherapy with R-CHOP regimen. (D) Comparing previous bronchoscopic finding. Slight flat bilobulated nodule was more decreased at about 5cm above carina after additional RT was done.
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