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Abstract
Umbilical cord blood (CB) is increasingly used as a source of stem cells to repopulate bone marrow in the treatment of life-threatening diseases in children and adults. I review the relationship between the placenta and circulating CB stem cells for hematopoiesis, the clinical results of cord blood stem cell transplantation, and I particularly emphasizethe criteria of CB donor choice. The scientific progress for the use of CB has resulted in the organization of CB banks all over the world. I also review the status of CB banks and networking systems worldwide as recipients of government-based political support.
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Fig. 2
Cytokine production from placenta and interaction with hematopoietic stem cells in fetal circulation.
Table 1.
NetCORD inventory and use on June, 2007
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