A Case of Infective Endocarditis associated with Microcytic Hypochromic Anemia

You-Kyong OH; Seok-In Hong; Myoung-Joon Song; Yeon-Seong Kim; Ki-Wook Chang; Hyun Suk Chae; Hyegung Lee; Seok Goo Cho

doi:10.5045/kjh.2005.40.3.201

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OH, Hong, Song, Kim, Chang, Chae, Lee, and Cho: A Case of Infective Endocarditis associated with Microcytic Hypochromic Anemia

Case Report

Korean J Hematol 2005;40(3):201-204.

Published online: 21 September 2005

DOI: https://doi.org/10.5045/kjh.2005.40.3.201

A Case of Infective Endocarditis associated with Microcytic Hypochromic Anemia

You-Kyong OH, M.D.¹, Seok-In Hong, M.D.¹, Myoung-Joon Song, M.D.¹, Yeon-Seong Kim, M.D.¹, Ki-Wook Chang, M.D.², Hyun Suk Chae, M.D.³, Hyegung Lee, M.D.⁴, Seok Goo Cho, M.D.¹

¹Division of Hematology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea

²Division of Cardiology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea

³Division of Gastroenterology, Department of Internal Medicine, The Catholic University of Korea, Seoul, Korea

⁴Department of Clinical Laboratories, College of Medicine, The Catholic University of Korea, Seoul, Korea

Correspondence to: Seok Goo Cho, M.D., Ph.D. Division of Hematology, Department of Internal Medicine, Catholic Hematopoietic Stem Cell Transplantation, St. Mary's Hospital, The Catholic University of Korea #62, Youido-dong, Yeongdeungpo-gu, Seoul 150-713, Korea Tel: +82-2-3779-1130, Fax: +82-2-780-3132 E-mail: chosg@catholic.ac.kr

Received 1 July 2005 Revised 9 September 2005 Accepted 9 September 2005

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We experienced a case of infective endocarditis, which unusual has symptoms and microcytic hypochromic anemia. Anemia associated with infective endocarditis is a common manifestation, but is generally normocytic nor-mochromic. However, microcytic hypochromic anemia is an uncommon manifestation of infective endo-carditis, and has only been noted in a few previous reports. We systematically evaluated anemia, and diagnosed fatal underlying diseases, such as infective endocarditis.

Keywords: Infective endocarditis, Microcytic hypochromic anemia

REFERENCES

1). Mylonakis E, Calderwood SB. Infective endocarditis in adults. N Engl J Med. 2000; 345:1318–30.

2). Krasnik L, Ochotny R, Hryniewiecki T, Paluszak J, Cieslinski A, Paradowski S. The level of erythropoietin in serum of patients with anemia during infective endocarditis. Pol Arch Med Wewn. 1999; 101:113–5.

3). Prendergast BD. Diagnostic criteria and problems in infective endocarditis. Heart. 2004; 90:611–3.

4). Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med. 2003; 352:1011–23.

5). Joyce RA, Sande MA. Mechanism of anemia in experimental bacterial endocarditis. Scand J Haematol. 1975; 15:306–11.

6). Huang HL, Lin FC, Hung KC, Wang PN, WU D. Hemolytic anemia in native valve infective endocarditis: a case report and literature review. Jpn Circ J. 1999; 63:400–3.

7). Prendergast BD. Diagnosis of infective endocarditis. BMJ. 2002; 325:845–6.

8). Hoen B, Selton-Suty C, Lacassin F, et al. Infective endocarditis in patients with negative blood cultures: analysis of 88 cases from a one-year nation wide survey in France. Clin Infect Dis. 1995; 20:501–6.

9). Spach DH, Kanter AS, Daniels NA, et al. Bartonella (Rochalimaea) species as a cause of apparent culture-negative endocarditis. Clin Infect Dis. 1995; 20:1044–7.

10). Houpikian P, Raoult D. Diagnostic methods current best practices and guidelines for identification of difficult-to-culture pathogens in infective endocarditis. Infect Dis Clin North Am. 2002; 16:377–92.

11). Moreillon P, Que YA. Infective endocarditis. Lancet. 2004; 363:139–49.

Fig. 1.

ChestX-ray. Chestx-ray showsmildcardiomegaly.

Fig. 2.

ChestX-ray. Chestx-ray showsmoreaggravated cardiomegalyandpulmonaryedema.

Fig. 3.

Two-dimensional echocardiogram. Parasternal long axis view. Freely mobile 22.8mm sized vegetation (arrowhead) attached to Rt. coronary cusp (LA, left atrium; LV, left ventricle; Ao, aorta).

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