Journal List > J Korean Assoc Oral Maxillofac Surg > v.37(6) > 1032510

J Korean Assoc Oral Maxillofac Surg. 2011 Dec;37(6):505-509. Korean.
Published online December 27, 2011.
Copyright © 2011 by The Korean Association of Oral and Maxillofacial Surgeons
Epithelial-myoepithelial carcinoma on the superficial lobe of the parotid gland: a case report
Sun-Mi Jin, Hyun-Ho Ryu, Seok-Hwan Ryu, Dong-Yoon Shin, Hie-Sung Hwang, Chul-Hoon Kim and Bok-Joo Kim
Department of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center, Busan, Korea.

Corresponding author: Bok-Joo Kim. Department of Oral and Maxillofacial Surgery, Department of Dentistry, Dong-A University Medical Center, Dongdaeshin-dong 3-1, Seo-gu, Busan 602-103, Korea. TEL: +82-51-240-5470, FAX: +82-51-241-5475, Email:
Received June 02, 2011; Revised August 30, 2011; Accepted October 12, 2011.


Epithelial-myoepithelial carcinoma (EMC) is a low-grade malignant salivary gland neoplasm that was first described in 1972. EMC occurs in the older age group, there is a female predilection and mainly involves the parotid gland. Most authors recommend superficial parotidectomy as a treatment for low-grade malignant tumor in the superficial lobe of parotid gland. The treatment of epithelial-myoepithelial tumors typically includes surgical excision aimed at achieving a R0 resection. This paper reports a case of EMC of the parotid gland treated only by a conservational surgical excision. The lesion was exposed by the retromandibular approach and detached. After the parotid gland envelop was exposed, the mass was observed and was easy to remove due to capsulation. The preoperative diagnosis was a pleomorphic adenoma on the left parotid gland. The tumor was removed surgically with a conservative extracapsular dissection. The postoperative diagnosis was EMC, so superficial parotidectomy or radiation therapy was considered. Nevertheless, the patient was observed and no additional treatment was attempted because the patient was old and a successfully excision of the tumor had been achieved.

Keywords: Epithelial-myoepithelial carcinoma; Parotid gland


Fig. 1
Facial view illustrating the 3-4 cm swelling on patient's left cheek.
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Fig. 2
Computed tomography (CT) scan. A. Transverse view of CT scan. B. Coronal view of CT scan.
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Fig. 3
Macroscopic view (external) shows well-circumscribed, thinly encapsulated mass with soft consistency.
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Fig. 4
Macroscopic view (cross section) shows a relatively well defined grayish white soft tissue mass with focal cystic change on sectioning. The tumor is confined to the gland.
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Fig. 5
Microscopic view (H&E staining, ×100). The parotid gland mass is composed of double layered tubules and solid area of clear cells (short arrows). The tubules are lined by inner cuboidal cells with eosinophilic cytoplasm and outer layer of clear, myoepithelial type cells (long arrow).
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Fig. 6
Microscopic view (H&E staining, ×40). The tumor also shows cystic area with papillary fronds (arrows).
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Fig. 7
The immunohistochemical stain confirms the outer layer of tubules are lined by p63 positive myoepithelial cells (arrows) (anti-p63 immunohistochemistry, ×100).
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