Relapsed extranodal NK/T-cell lymphoma in the mandible, Nasal Type: a case report and review of the literatures

Young-Wook Park; Yong-Tae Park; Kyo-Hee Choi; Seong-Gon Kim

doi:10.5125/jkaoms.2011.37.4.329

Journal List > J Korean Assoc Oral Maxillofac Surg > v.37(4) > 1032485

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Park, Park, Choi, and Kim: Relapsed extranodal NK/T-cell lymphoma in the mandible, Nasal Type: a case report and review of the literatures

Original Article

J Korean Assoc Oral Maxillofac Surg 2011;37(4):329-332.

Published online: 7 January 2011

DOI: https://doi.org/10.5125/jkaoms.2011.37.4.329

Relapsed extranodal NK/T-cell lymphoma in the mandible, Nasal Type: a case report and review of the literatures

Young-Wook Park¹, Yong-Tae Park¹, Kyo-Hee Choi², Seong-Gon Kim¹

¹Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University, Gangneung, Korea

²Department of Dentistry, College of Medicine, Hallym University, Chuncheon, Korea

^∗ This study was supported by a grant of the Korea Health 21 R&D Project Ministry of Health and Welfare, Republic of Korea.(A080293)

Seong-Gon Kim Department of Oral and Maxillofacial Surgery, College of Dentistry, Gangneung-Wonju National University 120 GangneungDaehag-ro, Gangneung, 210-320, Korea TEL: +82-33-640-2468 FAX: +82-33-640-3113 E-mail: epker@chollian.net

Received 20 April 201122 July 2011 Accepted 26 July 2011

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Extranodal NK/T-cell lymphoma (NTCL), nasal type is rare and highly fatal malignant neoplasm. Early diagnosis and establishing treatment plan are very difficult. Furthermore, NTCL in the mandible is an extremely rare condition. The clinical significance of presented case is the very rare location of NTCL. To the best of author’ s knowledge, this is the first reported case of NTCL of the mandible in the literature.

Keywords: Extranodal NK/T-cell lymphoma, Mandible, Epstein-Barr virus, CD56, Granzyme-B

REFERENCES

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Fig. 1.

Intraoral presentation of the lesion. The presented line showed a planned resection margin.

Fig. 2.

Magnetic resonance imaging of the lesion showed highly enhanced lesion in the mandible.(arrow)

Fig. 3.

The findings of immunohistochemistry and in situ hybridization. A. CD 3.(immunohistochemical staining, original magnification ×200), B. CD 30.(immunohistochemical staining, original magnification ×400), C. CD 56.(immunohistochemical staining, original magnification ×400), D. In situ hybridization for Epstein-Barr virus.(original magnification ×100), E. Granzyme B.(immunohistochemical staining, original magnification ×400), F. Ki67.(immunohistochemical staining, original magnification ×400)

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