Journal List > J Korean Assoc Oral Maxillofac Surg > v.36(6) > 1032434

Kim, Hur, Kim, Yang, Jeoung, Kook, Oh, Ryu, and Park: The effect of conservative neck dissection in the patients with oral cancer

Abstract

Introduction

This study examined the effect of a conservative neck dissection in patients with head and neck cancer.

Materials and Methods

A total of 24 patients, who underwent a conservative neck dissection for the treatment of oral cancer from January 2002 to December 2007, were included. All procedures were performed by one oral and maxillofacial surgeon. The mean age was 58.2 years (range, 19 to 79 years). The medical recordings, pathologic findings, and radiographic findings were evaluated. The mean follow up period was 41.1 months (range, 4 to 88 months).

Results

  1. Oral cancer was more common in men than women with a 3:1 ratio.

  2. Histopathologically, squamous cell carcinoma(83%) was the most prevalent oral cancer in this study.

  3. The most common primary site was the tongue(6 cases, 25%) followed by the mouth floor (5 cases, 21%), buccal mucosa (3 cases, 13%), lower lip, mandible, palate (2 cases, respectively) and salivary gland, retromolar area, oropharynx, alveolus (1 case, each).

  4. Three out of the 24 (13%) subjects had a recurrence at the primary sites.

  5. Two out of 24 (8%) subjects had a distant metastasis.

  6. All 24 patients survived and there were eleven patients who passed 5 years postoperatively.

Conclusion

A conservative neck dissection is a reliable and effective method for controlling neck node metastases in patients with oral cancer of the N0 or N1 neck node without serious complications.

REFERENCES

1. Crile G. Excision of cancer of the head and neck. With special reference to the plan of dissection based on 132 operations. JA-MA. 1906; 47:1780–5.
2. Martin H, Del Valle B, Ehrlich H, Cahan WG. Neck dissection. Cancer. 1951; 4:441–99.
crossref
3. Shaha AR. Radical neck dissection. Oper Tech Gen Surg. 2004; 6:72–82.
crossref
4. Soo KC, Guiloff RJ, Oh A, Della Rovere GQ, Westbury G. Innervation of the trapezius muscle: a study in patients undergoing neck dissections. Head Neck. 1990; 12:488–95.
crossref
5. Dulguerov P, Soulier C, Maurice J, Faidutti B, Allal AS, Lehmann W. Bilateral radical neck dissection with unilateral internal jugular vein reconstruction. Laryngoscope. 1998; 108:1692–6.
crossref
6. Sua ′ rez O. El problema de las metastasis linfa ′ ticas y alejadas del ca ′ ncer de laringe e hipofaringe. Rev Otorrinolaringol. 1963; 23:83–99.
7. Bocca E. Conservative neck dissection. Laryngoscope. 1975; 85:1511–15.
crossref
8. Robbins KT, Medina JE, Wolfe GT, Levine PA, Sessions RB, Pruet CW. Standardizing neck dissection terminology. Official report of the Academy's Committee for Head and Neck Surgery and Oncology. Arch Otolaryngol Head Neck Surg. 1991; 117:601–5.
crossref
9. O’ Brien CJ, Urist MM, Maddox WA. Modified radical neck dissection. Terminology, technique, and indicaction. Am J Surg. 1987; 153:310–6.
10. Medina JE, Byers RM. Supraomohyoid neck dissection: rationale, indications, and surgical technique. Head Neck. 1989; 11:111–22.
crossref
11. Medina JE. A rational classification of neck dissections, Otolaryngol Head Neck Surg. 1989; 100:169–76.
12. Shah JP. Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. Am J Surg. 1990; 160:405–9.
crossref
13. Byers RM. Modified neck dissection. A study of 967 cases from 1970 to 1980. Am J Surg. 1985; 150:414–21.
14. Byers RM, Wolf PF, Ballantyne AJ. Rationale for elective modified neck dissection. Head Neck Surg. 1988; 10:160–7.
crossref
15. Yousem DM, Som PM, Hackney DB, Schwaibold F, Hendrix RA. Central nodal necrosis and extracapsular neoplastic spread in cervical lymph nodes: MR imaging versus CT. Radiology. 1992; 182:753–9.
crossref
16. Hao SP, Ng SH. Magnetic resonance imaging versus clinical palpation in evaluating cervical metastasis from head and neck cancer. Otolaryngol Head Neck Surg. 2000; 123:324–7.
crossref
17. Houck JR, Medina JE. Management of cervical lymph nodes in squamous carcinomas of the head and neck. Semin Surg Oncol. 1995; 11:228–39.
crossref
18. Ali S, Tiwari RM, Snow GB. False-positive and false negative neck nodes. Head Neck Surg. 1985; 8:78–82.
19. Desanto LW, Beahrs OH. Modified and complete neck dissection in the treatment of squamous cell carcinoma of the head and neck. Surg Gynecol Obstet. 1988; 167:259–69.
20. Friedman M, Mafee MF, Pacella BL Jr, Strorigl TL, Dew LL, Toriumi DM. Rationale for elective neck dissection in 1990. Laryngoscope. 1990; 100:54–9.
crossref
21. Yu MG, Ryu SY. Usefulness of 18F-FDG PET/CT in the evaluation of cervical lymph node metastasis in patients with oral cancer. J Korean Assoc Oral Maxillofac Surg. 2009; 35:213–20.
22. Belhocine T, Spaepen K, Dusart M, Castaigne C, Muylle K, Bourgeois P, et al. 18FDG PET in oncology: the best and the wost (Review). Int J Oncol. 2006; 28:1249–61.
23. Bray F, Sankila R, Ferlay J, Parkin DM. Estimates of cancer incidence and mortality in Europe in 1995. Eur J Cancer. 2002; 38:99–166.
crossref
24. Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for squamous cell carcinoma of the oral cavity in young people-a comprehensive literature review. Oral Oncol. 2001; 37:401–18.
25. Hindle I, Downer MC, Speight PM. The epidermiology of oral cancer. Br J Oral Maxillofac Surg. 1996; 34:471–6.
26. Arbes SJ Jr, Olshan AF, Caplan DJ, Schoenbach VJ, Slade GD, Symons MJ. Factors contributing to the poorer survival of black Americans diagnosed with oral cancer (United states). Cancer Causes Control. 1999; 10:513–23.
27. Shiboski CH, Shiboski SC, Silverman S Jr. Trends in oral cancer rates in the United States, 1973-1996. Community Dent Oral Epidemiol. 2000; 28:249–56.
crossref
28. Chandu A, Adams G, Smith AC. Factors affecting survival in patients with oral cancer: an Australian perspective. Int J Oral Maxillofac Surg. 2005; 34:514–20.
crossref
29. Lung T, Ta ̆s ¸ ca ̆u OC, Alma ̆s ¸ an HA, Mures ¸ an O. Head and neck cancer, epidemiology and histological aspects-Part 1: a decade’ s results 1993-2002. J Craniomaxillofac Surg. 2007; 35:120–5.
30. Cho JH, Kim CS. Clinical and statistical analysis of the oral cancer patients: a statistical analysis of 256 cases. J Korean Assoc Maxillofac Plast Reconstr Surg. 1998; 20:33–44.
31. Funk GF, Karnell LH, Robinson RA, Zhen WK, Tras DK, Hoffman HT. Presentation, treatment, and outcome of oral cavity cancer: a National Cancer Data Base report. Head Neck. 2002; 24:165–80.
crossref
32. Hindle I, Nally F. Oral Cancer: a comparative study between 1962-67 and 1980-84 in England and Wales. Br Dent J. 1991; 170:15–20.
crossref
33. Budhy TI, Soenarto SD, Yaacob HB, Ngeow WC. Changing incidence of oral and maxillofacial tumours in East Java, Indonesia, 1987-1992. Part 2: malignant tumours. Br J Oral Maxillofac Surg. 2001; 39:460–4.
crossref
34. Rawashdeh MA, Matalka I. Malignant oral tumors in Jordanians, 1991-2001. A descriptive epidemiological study. Int J Oral Maxillofac Surg. 2004; 33:183–8.
crossref
35. Khafif RA, Gelbfish GA, Asase DK, Tepper P, Attie JN. Modified radical neck dissection in cancer of the mouth, pharynx, and larynx. Head Neck. 1990; 12:476–82.
crossref
36. Chu W, Strawitz JG. Results in suprahyoid, modified radical, and standard radical neck dissections for metastatic squamous cell carcinoma: recurrence and survival. Am J Surg. 1978; 136:512–5.
crossref
37. Hao SP, Tsang NM. The role of supraomohyoid neck dissection in patients of oral cavity carcinoma (small star, filled). Oral Oncol. 2002; 38:309–12.
38. Chan SW, Mukesh BN, Sizeland A. Treatment outcome of N3 nodal head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg. 2003; 129:55–60.
crossref

Table 1.
Types of primary tumor
Type Number
Squamous cell carcinoma 20
Adenoid cystic carcinoma 1
Basal cell carcinoma 1
Verrucous carcinoma 1
Osteosarcoma 1
Table 2.
Location of primary tumor
Location Number
Mouth floor 5
Salivary gland 1
Lower lip 2
Tongue 6
Retromolar area 1
Buccal mucosa 3
Mandible 2
Oropharynx 1
Alveolus 1
Palate 2
Table 3.
Summary of patients
No. Stage Operation Neck dissection 1st visit - OP (days) F/U period (months) Recurrence Metastssis
1 T2N0M/T2N0M0 Tr, WSE, R Both SOHND 15 18 N N
2 T3N0M0/T3N0M0 G, MM, R Rt. SOHND, Lt. SHND 6 88 N N
3 T2N0M0/T2N0M0 Tr, G, MM, R Both SOHND 15 63 N N
4 TxN0M0/TxN0M0 P, SM, R Lt. SOHND 13 45 N N
5 T2N0M0/T2N0M0 WSE, R Lt. SOHND 22 62 N N
6 T3N0M0/T3N0M0 G Lt. SOHND 8 21 N N
7 T2N0M0/T2N0M0 WSE, R Lt. SOHND 14 39 N N
8 T3N0M0/T3N0M0 G, R Lt. SOHND 8 49 N N
9 T2N0M0/T2N0M0 M, R Rt. SOHND 8 43 N N
10 T2N0M0/T3N0M0 M Rt. SOHND 8 38 N N
11 T2N1M0/T2N0M0 WSE, R Both SOHND 10 27 N N
12 T3N2bM0/T3N0M0 Tr, G, SM, R Both FND 82 77 N N
13 T4N2cM0/T3N0M0 G, WSE Both SOHND 5 76 N N
14 T4N2bM0/T1N0M0 Tr, SM, G, WSE, R Rt. SHND, Lt. SOHND 13 35 Y N
15 T2N1M0/T2N0M0 WSE, R Lt. SOHND 9 27 N N
16 T4N2bM0/T3N0M0 Tr, SM Rt. FND, Lt. SOHND 10 41 N N
17 T3N0M0/T3N1M0 WSE, SM, R Lt. FND. Rt. SOHND 7 4 Y N
18 T3N0M0/T3N1M0 Tr, WSE, MM, R Lt. FND 36 39 N N
19 T3N0M0/T3N2bM0 Tr, SM Both FND 17 28 N N
20 T2N1M0/T2N2aM0 Tr, MM, WSE, R Both SOHND 14 35 N Y
21 T2N1M0/T1N2cM0 G, R Lt. SOHND, Rt. FND 14 44 N Y
22 T2N1M0/T2N2aM0 SM, G, R Lt. MRND, Rt. SOHND 28 25 Y N
23 T2N1M0/T4N2bM0 Tr, SM, WSE, R Rt. FND, Lt. SOHND 10 39 N N
24 T3N1M0/T4N2bM0 Tr, SM, WSE, R Lt. FND 12 24 N N

(Tr: tracheostomy, WSE: wide surgical excision, R: reconstruction, G: glossectomy, MM: marginal mandibulectomy, P: parotidectomy, SM: segmental mandibulectomy, M: maxillectomy, SOHND: supraomohyoid neck dissection, FND: functional neck dissection, SHND: suprahyoid neck dissection, MRND: modified RND, OP: operation, F/U: follow up)

Table 4.
Summary of recurred patients
No. Neck dissection Radiotherapy Involved neck node Primary recurrence Neck metastasis Period to recurrence (months) Distant Metastasis (months) Post treatment
20 Both SOHND X Lt. Ia   Lt. II, intraparotid 34 Liver (34) 6th CT
21 Lt. SOHND, Rt. FND Post OP RT Lt. Ib     5 Lung (5) RT
14 Rt. SHND, Lt. SOHND Post OP RT X Oropharynx   6 17 X FND, RT, CT
17 Lt. FND, Rt. SOHND Post OP RT Lt. Ia Lt. parotid   2 X RT
22 Lt. MRND, Rt. SOHND Post OP RT Lt. II Mouth floor   22 X FND, RT

(SOHND: supraomohyoid neck dissection, FND: functional neck dissection, SHND: suprahyoid neck dissection, OP: operation, MRND: modified RND, RT: radiotherapy, CT: chemotherapy)

TOOLS
Similar articles