Abstract
Purpose
Materials and Methods
Results
Figures and Tables
Fig. 1
Examples of nodules suspected as malignant on US findings. (A) A 6-mm suspicious nodule (delineated by electronic calipers) was found on the right thyroid gland, and PTC was confirmed by surgical pathology. (B) A 7-mm suspicious nodule (delineated by electronic calipers) was found on the right thyroid gland and was cytologically confirmed as FLT more than twice by FNAB. The thyroid gland showed diffuse heterogeneous echogenicity, a characteristic finding of the DTD pattern of thyroid gland on US. (C) There was a 6-mm suspicious nodule (delineated by electronic calipers) on the left thyroid gland, which was cytologically confirmed as AH more than twice by FNAB. PTC, papillary thyroid cancer; FLT, focal lymphocytic thyroiditis; AH, adenomatous hyperplasia; FNAB, fine needle aspiration biopsy; DTD pattern, "diffuse thyroid disease" pattern on US; US, ultrasound.
![ymj-56-1338-g001](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-g001.jpg)
Table 1
Baseline Characteristics According to Cytological Diagnosis
![ymj-56-1338-i001](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-i001.jpg)
FLT, focal lymphocytic thyroiditis; AH, adenomatous hyperplasia; PTC, papillary thyroid cancer; US, ultrasound; DTD pattern, "diffuse thyroid disease" pattern on US; TSH, thyrotropin; Tg-Ab, thyroglobulin antibody; TPO-Ab, thyroid peroxidase antibody.
Data are mean±SD or number of patients (%). p value by one-way ANOVA for continuous variables and χ2-test for categorical variables.
*p<0.05, †p<0.01, ††p<0.001, the comparison of the FLT or AH group with the PTC group, §The portion of the patients treated with levothyroxine or anti-thyroid drugs, ∥Comparison between the absence and the presence of calcification.
Table 2
Clinical, Biochemical, and Sonographic Characteristics of the FLT Group, Compared with the PTC Group, According to Nodule Size
![ymj-56-1338-i002](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-i002.jpg)
PTC, papillary thyroid cancer; FLT, focal lymphocytic thyroiditis; TSH, thyrotropin; Tg-Ab, thyroglobulin antibody; TPO-Ab, thyroid peroxidase antibody; DTD pattern, "diffuse thyroid disease" pattern on US; US, ultrasound.
Data are mean±SD or number of patients (%). p value by Student's t-test or Mann-Whitney U test for continuous variables and χ2-test or Fisher exact test for categorical variables.
*The portion of the patients treated with levothyroxine or anti-thyroid drugs.
Table 3
Univariate and Multivariate Analysis among Groups
![ymj-56-1338-i003](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-i003.jpg)
Table 4
Univariate and Multivariate Analysis between the FLT Group and the PTC Group According to Nodule Size
![ymj-56-1338-i004](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-i004.jpg)
Table 5
Predictor Model of FLT from PTC Based on Individual or Combined Variables
![ymj-56-1338-i005](/upload/SynapseData/ArticleImage/0069ymj/ymj-56-1338-i005.jpg)
References
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