Journal List > Yonsei Med J > v.54(5) > 1031136

Lee and Kang: Human Infection of Salmonella Matadi in Korea
To the Editor: Salmonella Matadi (S. Matadi) was firstly isolated in 19541 from Matadi, the regional capital of Belgian Congo which was the former name of Democratic Republic of the Congo. This is a very rare serotype, and a few cases have been reported in Denmark during 1960 and 19682 and USA in 1993,3 although the incidence of S. Matadi has recently increased in USA, Canada and Japan. Reptile is regarded as a source of infection, particularly the intestine of adult female iguana,4 and there is also a report on the infection of 2 teenage boys who handled a green iguana.3
In Korea, S. Matadi was first isolated recently from 15-month old baby who suffered from severe fever and mucous diarrhea for 5 days. Cefotiam as antimicrobial and general medicines for intestinal disorder were given as the first treatments on 5 days after symptom appeared. However, fever and diarrhea continued until cefotaxime treatment on 7 days after the appearance of the symptoms.
S. Matadi was isolated from diarrhea samples and its serotype was determined by agglutination test and MLST. Hematological test was performed twice; on the day of hospitalization and second treatment. MCV, MCH and Hb showed relatively low rate, compared with normal range, indicating dehydrated body condition. S. Matadi was susceptible, but not resistant to antimicrobial agents that were given along with 17 agents which are generally used for Enterobactericeae.
Cefotiam is a good antimicrobial agent, however, it may not be appropriate choice to treat Salmonella spp. infection. It is not clear how 15-month old baby was infected with S. Matadi: whether through infected reptile or contaminated food. He was too young and fed only powdered milk and weaning food. He was not in nursing facility or did not travel foreign country. His family members did not bring in any reptiles as a pet and did not show similar symptoms. However, his father was suspected as carrier because he worked in the import and export shipments Co. at Busan port and used to handle luggage by hands. Susceptibility of Salmonella infection in children younger than five years of age is five times higher than in adults. Therefore, small amount of S. Matadi in father's hand might have infected 15-month old baby who was more sensitive than his parents.
In recent years, new Salmonella serovar has often been brought in from other countries by travelers, such as S. Wandsworth from Vietnam to Korea in 2012. Such cases are not common, nevertheless, the possibility is increasing because of increase of international trade.

References

1. Kauffmann F, Vandepitte J. Two new Salmonella types (S. limete and S. Matadi) from the Belgian Congo. Acta Pathol Microbiol Scand. 1954; 34:97–98.
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2. Grunnet K, Nielsen BB. Salmonella types isolated from the gulf of Aarhus compared with types from infected human beings, animals, and feed products in Denmark. Appl Microbiol. 1969; 18:985–990.
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3. Ackman DM, Drabkin P, Birkhead G, Cieslak P. Reptile-associated salmonellosis in New York State. Pediatr Infect Dis J. 1995; 14:955–959.
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4. Mitchell MA, Shane SM. Preliminary findings of Salmonella spp. in captive green iguanas (Iguana iguana) and their environment. Prev Vet Med. 2000; 45:297–304.
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