The number and sizes of corneocytes in 10 different sites on young, healthy adults of both sexes were estimated, using the detergent scrub technique and an automatic cytographic counter. At all collection sites the count was higher in the males-significantly so at all sites except the palm and cubital fossa. At all collection sites except the popliteal fossa and the heel, the corneocytes were larger in the females-significantly so at the cubital fossa, medial upper arm, abdomen, and back sites.