Journal List > Yonsei Med J > v.24(1) > 1028211

Choi, Cho, and Kim: Hereditary Spastic Paraplegia

Abstract

Hereditary spastic paraplegia (HSP) is a rare hereditary disorder and becomes clinically apparent during adolescence or in childhood and progresses s1owly throughout the adult years with a variability in the severity of expression.
We experienced 3 cases of hereditary spastic paraplegia. Cases 1 and 2, which were pure HSP, had only the signs and symptoms of corticospinal tract involvement with the positive family history, and case 3, which was a complicated case of HSP, had distal muscle wasting, dysarthria, signs and symptoms of the corticospinal tracts, and a positive family history.
All are thought to be inherited in an autosomal dominant pattern.

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