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Kim, Choi, and Kim: HLA-DR Antigens and HLA-B: DR Haplotypes in Koreans
Original Article

Yonsei Medical Journal 1983; 24(1): 33-37.

Published online: 20 February 2002

DOI: https://doi.org/10.3349/ymj.1983.24.1.33

HLA-DR Antigens and HLA-B: DR Haplotypes in Koreans

Se Jong Kim, In Hong Choi, Joo Duek Kim

Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea.

Received 7 February 1983

Copyright © 1983 The Yonsei University College of Medicine

Abstract

HLA-DR antigen and gene frequencies were studied in 150 unrelated Koreans in Seoul. HLA-DR4 was the most common DR specificity encountered and HLA-DR1 and -DR3 occurred with the lowest frequencies. The frequency of HLA-DR blank allele was 27.1%. HLA-B:DR haplotypes involving positive delta values differing significantly from zero were DR1:B7, DR2:Bw22, DR3:B17, DR5:Bw35, DRw6:B17, DR7:B12, DR7:B13, and DRw8:Bw16. The supertypic groups (MT1, MT2 and MT3) differ somewhat in frequencies from Other populations.
These findings suggested that the Korean population, while having many similarities in HLA-DR antigen frequencies with those of neighboring Orientals, has not only different features in the distribution of HLA-DR antigens but also has unique HLA-B:DR haplotypes.

Keywords: HLA-DR antigens, HLA-B:DR haplotypes, Korean

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ORCID iDs

In Hong Choi
https://orcid.org/http://orcid.org/0000-0001-9851-0137

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