Journal List > Yonsei Med J > v.2(1) > 1028103

TOOLS
Kang, Park, and Lee: Effect of Varying Hematocrit Ratio on the Gastric Acid Secretion
Original Article
Yonsei Medical Journal

Yonsei Medical Journal 1961; 2(1): 13-18.

Published online: 20 February 2002

DOI: https://doi.org/10.3349/ymj.1961.2.1.13

Effect of Varying Hematocrit Ratio on the Gastric Acid Secretion

Doo Hee Kang, Moon Jae Park**, Pyung Hee Lee

Department of Physiology Yonsei University College of Medicine, Seoul, Korea.

Current address:

**Department of Physiology, University of Minnesota. School of Medicine, Minneapolis, Minn., U.S.A.

Copyright © 1961 The Yonsei University College of Medicine

Abstract

Effect of varying hematocrit ratio on the gastric acid production was studied in the heart-stomach preparation of the frog. When the hematocrit ratio was raised by injecting packed red blood cells obtained from the same species of frog, the acid production was increased significantly as compared to the low hematocrit group in which hematocrit ratio was lowered by injecting frog's normal saline.
When a small amount of histamine was added to the medium of 25℃, the acid production was increased in all cases, but the difference in the acid production between the high and the low hematocrit groups was abolished. However, when the temperature of the medium was lowered to 15℃, the differences in the acid production between the two groups became significant.
When a large amount of acetazolamide was added to the medium at 25℃, the acid production was decreased significantly in both groups without showing a significant difference between the two groups.
The reason(s) responsible for the increased acid production in the high hematocrit group was discussed.

TOOLS
Similar articles