In 2016, the editors invited many reviewers over the world and 677 reviewers accepted the invitation and sent back their comments. I, as Editor-in-Chief of the Journal of Korean Medical Science (JKMS), sincerely appreciate their professional efforts and contributions. The JKMS published 352 articles in the volume 31 by 12 regular and 2 supplementary issues in 2016. The submissions from December 2015 to November 2016 were 1,214, 401 (33.0%) of them were contributed by overseas authors. The acceptance rate was 20.3% in 2016. The Journal Impact Factor 2015 by the Journal Citation Reports® was reported 1.256 by the Thomson Reuters, which was on the 49.6% position among 155 journals in the category of medicine in general and internal.