Abstract
Figures and Tables
Fig. 1
Histologic features of explanted lungs showing non-specific interstitial pneumonia (NSIP) with diffuse alveolar damage (DAD) pattern in a patient who clinically suggested with acute interstitial pneumonia. Diffuse interstitial thickening and chronic inflammatory cell infiltration are observed in both lobes, suggesting NSIP (A). In addition, focal DAD pattern is also observed in the right lobe (B) (Hematoxylin and eosin stain; original magnification: ×200).
![jkms-30-1439-g001](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-g001.jpg)
Fig. 2
Histologic features of end-stage lung from patients who received chemotherapy and peripheral blood stem cell transplantation. Diffuse and marked interstitial fibrosis with nearly complete loss of alveolar spaces and shrinkage of the lung tissue around a bronchus are observed (Hematoxylin and eosin stain; original magnification: (A) ×100, (B) ×400).
![jkms-30-1439-g002](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-g002.jpg)
Fig. 3
Survival curve based on the presence of pathologic diffuse alveolar damage (DAD) pattern using the Kaplan-Meier method with the log-rank test.
![jkms-30-1439-g003](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-g003.jpg)
Table 1
Clinicopathologic features of patients with lung transplantation and the clinical outcome
![jkms-30-1439-i001](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-i001.jpg)
F/U, follow-up; mo, month; TPL, transplantation; SLT, single lung transplantations; BSSLT, bilateral sequential single lung transplantations; HLT, heart-lung transplantation; DPLDs, diffuse parenchymal lung diseases; IPF, idiopathic pulmonary fibrosis; UIP, usual interstitial pneumonia; AIP, acute interstitial pneumonia; DAD, diffuse alveolar damage; NSIP, non-specific interstitial pneumonia; CVD-ILD, collagen-vascular disease-related interstitial lung disease; DM, dermatomyositis; RA, rheumatoid arthritis; LAM, lymphangioleiomyomatosis; Tb, tuberculosis; DPB, diffuse panbronchiolitis; PAH, Pulmonary arterial hypertension; PPH, primary pulmonary hypertension; IMA, invasive mucinous adenocarcinoma; GVHD, graft-versus-host disease; BO, bronchiolitis obliterans; IPS, idiopathic pneumonia syndrome; ARDS, acute respiratory distress syndrome; UnIP, unclassifiable interstitial pneumonia; DIC, disseminated intravascular coagulation.
Table 2
Perioperative factors of recipients with lung transplantation
![jkms-30-1439-i002](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-i002.jpg)
Table 3
Preoperative variables reflecting patients' severity based on the presence of pathologic diffuse alveolar damage (DAD) pattern
![jkms-30-1439-i003](/upload/SynapseData/ArticleImage/0063jkms/jkms-30-1439-i003.jpg)