Abstract
Autoimmune cholangitis (AC) is a recently proposed entity that describes a
specific group of patients presenting overlapping features of primary biliary
cirrhosis (PBC) and autoimmune hepatitis. The disease is characterized by
dinical cholestasis, high titer antinuclear antibody, negative antimitochondrial
antibody, and histologically, findings of PBC coexisting with varying degrees of
parenchymal inflammation. In this report, we describe a patient with Sjogren's
syndrome who fulfilled the diagnostic criteria of AC associated with unique
arthropathy compatible with arthritis of PBC. This case illustrates the unusual
coexistence of two diseases that may share similar pathogenic processes.