Abstract
We describe two cases of fetal atrial flutter associated with severe fetal
hydrops which were unresponsive to digoxin but were successfully treated with
flecainide acetate. Two cases of fetal atrial flutter were identified in fetuses
with severe fetal hydrops on 3rd trimester ultrasonogram(28 weeks' gestation and
30 weeks' gestation). Following failed digoxin monotherapy, flecainide acetate
was added to digoxin. On the 7th day and 13th day after combined therapy, fetal
heart rate converted to normal sinus rhythm without recurrence. Our cases showed
that the combined therapy of digoxin and flecainide acetate can effectively
treat fetal atrial flutter associated with fetal hydrops unresponsive to digoxin
monotherapy.