Abstract
We report a 27-year-old woman who developed Coombs' negative hemolytic anemia
and fulminant hepatic failure as the initial manifestation of Wilson's disease.
Unmeasurably low level of serum alkaline phosphatase provided a clue to the
diagnosis of Wilson's disease. The diagnosis was established with the presence
of Kayser-Fleischer ring, decreased serum ceruloplasmin level, and elevated
urine and serum copper levels. In spite of repeated plasmapheresis, she died of
multiorgan failure on the fifth hospital day.