‘Takotsubo cardiomyopathy’ or ‘stress-induced cardiomyopathy’ is a newly described clinical entity characterized by transient left ventricular apical ballooning and left ventricular apical dyskinesis in the absence of angiographic feature of significant coronary artery disease. The cause of takotsubo cardiomyopathy is unclear, but catecholamines probably play a role in the takotsubo cardiomyopathy. We report a case of pheochromocytoma-induced takotsubo cardiomyopathy that showed atypical pattern of reversed takotsubo cardiomyopathy with transient significant mitral regurgitation. This is the first case showing the reversal of takotsubo cardiomyopathy due to pheochromocytoma in Korea.