Incidence and Risk Factors of Retinal Detachment after Laser Photocoagulation in Anterior Zone I Retinopathy of Prematurity

Sang Woo Park; Jung Won Park; Dae Hyun Kim; Jae Kyoun Ahn; Yeoung Geol Park; Hwan Heo

doi:10.4068/cmj.2009.45.1.60

Journal List > Chonnam Med J > v.45(1) > 1017934

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Park, Park, Kim, Ahn, Park, and Heo: Incidence and Risk Factors of Retinal Detachment after Laser Photocoagulation in Anterior Zone I Retinopathy of Prematurity

Original Article

Chonnam Medical Journal

Chonnam Medical Journal 2009; 45(1): 60-65.

Published online: 27 April 2009

DOI: https://doi.org/10.4068/cmj.2009.45.1.60

Incidence and Risk Factors of Retinal Detachment after Laser Photocoagulation in Anterior Zone I Retinopathy of Prematurity

Sang Woo Park, Jung Won Park, Dae Hyun Kim¹, Jae Kyoun Ahn, Yeoung Geol Park, Hwan Heo

Department of Ophthalmology, Chonnam National University Medical School and Hospital, Gwangju, Korea.

¹Department of Ophthalmology, College of Medicine, Chosun University, Gwangju, Korea.

opheye@hanmail.net

Accepted 16 February 2009

Abstract

The aim of this study was to evaluate the incidence and risk factors of retinal detachment after laser photocoagulation therapy in anterior zone I retinopathy of prematurity (ROP). We performed a retrospective analysis of records of 30 eyes (16 patients) with threshold anterior zone I ROP that were treated with diode laser photocoagulation. We investigated the incidence and time of retinal detachment, birth weight, gestational age, systemic problem, vitreous hemorrhage, the interval between diagnosis of first ROP and threshold ROP, and the number of laser burns. We performed statistical analysis of the risk factors. The total incidence rate of retinal detachment was 43.3% (13 eyes), and the mean time was 2.85±2.88 (range: 1~12) weeks after laser photocoagulation. There were no significant differences in birth weight, gestational age, systemic problem, the interval between diagnosis of first ROP and threshold ROP, or the number of laser burns between the retinal detachment group and no retinal detachment group. The incidences of vitreous hemorrhage in the retinal detachment group and no retinal detachment group were 46.2% (6 eyes) and 5.9% (1 eye), respectively (p=0.04). The results suggest that vitreous hemorrhage is a risk factor for retinal detachment in threshold anterior zone I ROP after laser photocoagulation therapy. Vitreous hemorrhage should be regarded as a sign of poor prognosis and it is necessary to follow up carefully.

Keywords: Retinal detachment, Retinopathy of prematurity, Risk factors

Figures and Tables

Fig. 1

Time-event diagrams of events occurring after diode laser treatment of threshold anterior zone I retinopathy of prematurity for developing a retinal detachment. ^*ROP, retinopathy of prematurity; ^†RD, retinal detachment.

Table 1

Comparison of risk factors between retinal detachment group and no retinal detachment group after laser photocoagulation treated for threshold anterior zone I retinopathy of prematurity

^*ROP, retinopathy of prematurity; ^†RD, retinal detachment.

Table 2

Univariate and multivariate logistic regression model of risk factors associated with retinal detachment among eyes treated for threshold anterior zone I retinopathy of prematurity

^*OR, Odds ratio; ^†ROP, Retinopathy of prematurity.

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