Relationship of Colorectal Polyps and the Risk Factors Including Obesity, Age, Alcohol and Smoking

Hyun-Min Lee; Soong Lee; Jae-Kyu Lim; Jang-Won Seo; Ki-Sang Lee; Seung-Chul Baek; Yun-Cheol Kim; Byung-Chul Shin; Sin-Ok Kang

doi:10.4068/cmj.2009.45.3.168

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Lee, Lee, Lim, Seo, Lee, Baek, Kim, Shin, and Kang: Relationship of Colorectal Polyps and the Risk Factors Including Obesity, Age, Alcohol and Smoking

Original Article

Chonnam Medical Journal

Chonnam Medical Journal 2009; 45(3): 168-174.

Published online: 10 December 2009

DOI: https://doi.org/10.4068/cmj.2009.45.3.168

Relationship of Colorectal Polyps and the Risk Factors Including Obesity, Age, Alcohol and Smoking

Hyun-Min Lee, Soong Lee, Jae-Kyu Lim, Jang-Won Seo, Ki-Sang Lee, Seung-Chul Baek, Yun-Cheol Kim, Byung-Chul Shin, Sin-Ok Kang¹

Department of Internal Medicine, College of Medicine, Seonam University, Gwangju, Korea.

¹Department of Internal Medicine, College of Medicine, Seonam University, Namkwang Hospital, Gwangju, Korea.

Corresponding author (lsmed@hanmail.net)

Accepted 25 November 2009

Abstract

Controversy remains over the role of risk factors in developing colorectal polyps. The aim of this study was to investigate the relationship of colorectal polyps with risk factors including obesity, age, alcohol, and smoking. We retrospectively assessed colorectal polyps through medical records and patient interviews of 1080 patients who underwent colonoscopy regardless of symptoms. The degree of obesity was determined by body mass index (BMI), and colorectal polyps were divided into hyperplastic and adenomatous polyps. The prevalence of colorectal polyps was 45.3% (489 patients). Of these, the prevalences of hyperplastic polyps and adenomatous polyps were 23.3% and 26.7%, respectively. The most common number, size, and location of colorectal polyps were one (63.8%), 5.0~9.0 mm (50.1%), and rectosigmoid colon (35.7%), respectively. Age, amount of alcohol, and smoking were significantly higher in the group with polyps than in that without polyps (54.9±11.3 vs. 50.0±13.1 years, 75.8 vs. 39.3 g/week, and 9.3±12.6 vs. 4.6±9.1 pack years, respectively, p=0.001). There were no significant differences in BMI between the groups with (23.2 kg/m²) or without (23.1 kg/m²) polyps. Also, there was no significant relationship between BMI and the size, number, or location of colorectal polyps. Age, alcohol, and smoking were associated with colorectal polyps by one-way ANOVA test but not by multivariate logistic regression analysis. Additionally, BMI had no relationship with the size, number, or location of colorectal polyps. In conclusion, age, alcohol drinking, and smoking may be associated with colorectal polyps, but obesity as assessed by BMI was not.

Keywords: Colonic polyps, Obesity, Age factor, Alcohol drinking, Smoking

Figures and Tables

Fig. 1

The correlation between the number of colorectal polyps and body mass index.

Fig. 2

The correlation between the size of colorectal polyps and body mass index.

Table 1

Characteristics of the subjects including age, sex, smoking and alcohol

^*By one way ANOVA test; SD, standard deviation; CI, confidence interval; ^†p value for the comparison between the polyp group and the polyp-free group; ^‡p value the comparison between hyperplastic and adenomatous polyps. ^§By multi-variate logistic regression analysis.

Table 2

Positive rate and characteristics of colorectal polyps

Table 3

Relationship between colorectal polyps and body mass index

^*By one way ANOVA test; BMI, body mass index; SD, standard deviation; CI, confidence interval; ^†p value for the comparison between the polyp group and the polyp-free group; ^‡p value for the comparison between hyperplastic and adenomatous polyps. ^§By multi-variate logistic regression analysis.

Table 4

Relationship between location of colorectal polyps and body mass index

^*By one way ANOVA test; BMI, body mass index; SD, standard deviation.

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