Journal List > J Korean Neuropsychiatr Assoc > v.54(4) > 1017753

Park and Kang: History of Schizophrenia

Abstract

Fundamental difficulties in psychiatric nosology lie in the most basic fact that it deals with subjective states of the human mind. Modern instrumental diagnostic classification systems, which amount to lists of symptom inventories, could not provide accurate concepts of psychiatric disorders. This is also true for schizophrenia, a representative mental disorder. Kraepelin's dementia praecox was a collection of controversially proposed diseases, which had some critical similarities in their clinical features, i.e., the course and outcome. Despite initial debates on the adequacy of this concept, dementia praecox was recognized as a disease entity quite early, so that the concept of dementia praecox or schizophrenia proliferated, became diversified, and was then altered. We can now find large discrepancies between Kraepelin's dementia praecox and today's schizophrenia. However, the myth of disease entity was seldom challenged and psychiatrists today implicitly believe that they are dealing with what Kraepelin had proposed. In order to navigate this impasse, we thought that historical studies on the concept of dementia praecox and underlying taxonomic principles established by 19th century alienists including Kraepelin would shed some light. The aim of this article is to comprehensively review the history of concepts of dementia praecox or schizophrenia, and to question critically how much today's schizophrenia has received the conceptual inheritance from original concepts. Through this process, we expect to attain a renewed understanding of schizophrenia.

Figures and Tables

Table 1

Symptoms comprising catatonia45)

jkna-54-365-i001
Table 2

Factor structure of catatonic symptoms

jkna-54-365-i002

ICD-10 criteria also includes rigidity, command automatism and perseveration. *: Item included in the criteria of ICD-10 catatonic schizophrenia, : In DSM-5, individual items are counted (total 12 items). ICD : Implantable cardioverter-defibrillator

Table 3

Characteristics of paranoid psychoses by Kraepelin [modified from Kendler and Tsuang (1981)76)]

jkna-54-365-i003

*: Delusional disorder in current diagnostic system. D para : Dementia paranoides, DP : Dementia praecox, DP para : Paranoid dementia praecox (paranoid dementia), hebe : Hebephrenia, cata : Catatonia

Table 4

Paranoid vs. non-paranoid (hebephrenic) schizophrenia [modified from Tsuang and Winokor (1974)80)]

jkna-54-365-i004

*: Criterion not applied

Table 5

Subtypes of dementia praecox per Kraepelin's textbook, 8th edition4)

jkna-54-365-i005
Table 6

Outcome of dementia praecox per Kraepelin's textbook, 8th edition4)

jkna-54-365-i006
Table 7

Some diagnostic criteria for schizophrenia

jkna-54-365-i007

FRS : Frist-rank symptoms, hebe : Hebephrenia, cata : Catatonia, deperson : Depersonalization, dereal : Derealization, RDC : Research Diagnostic Crieria, PSE : Present State Examination

Notes

Conflicts of Interest The authors have no financial conflicts of interest.

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