Quantitative Electroencephalography Findings in Attention-Deficit Hyperactivity Disorder According to Korean DISC-IV

Jun Won Kim; Hyun Jin Kim; Doug Hyun Han; Young Sik Lee; Kyung Joon Min; Kounseok Lee; Jaewon Lee

doi:10.4306/jknpa.2013.52.3.143

Journal List > J Korean Neuropsychiatr Assoc > v.52(3) > 1017624

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Kim, Kim, Han, Lee, Min, Lee, and Lee: Quantitative Electroencephalography Findings in Attention-Deficit Hyperactivity Disorder According to Korean DISC-IV

Original Article

Journal of Korean Neuropsychiatric Association

Journal of Korean Neuropsychiatric Association 2013; 52(3): 143-149.

Published online: 31 May 2013

DOI: https://doi.org/10.4306/jknpa.2013.52.3.143

Quantitative Electroencephalography Findings in Attention-Deficit Hyperactivity Disorder According to Korean DISC-IV

Jun Won Kim, MD^1,², Hyun Jin Kim, MD¹, Doug Hyun Han, MD, PhD³, Young Sik Lee, MD, PhD³, Kyung Joon Min, MD, PhD³, Kounseok Lee, MD⁴, Jaewon Lee, MD⁵

¹Department of Psychiatry, Gongju National Hospital, Gongju, Korea.

²Graduate School, Chung-Ang University, Seoul, Korea.

³Department of Psychiatry, College of Medicine, Chung-Ang University, Seoul, Korea.

⁴Department of Psychiatry, Samsung Medical Center, Seoul, Korea.

⁵Department of Psychiatry, Gangnam Eulji Hospital, Eulji University, Seoul, Korea.

Address for correspondence: Jaewon Lee, MD. Department of Psychiatry, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 137-710, Korea. Tel +82-2-3438-1121, Fax +82-2-3438-1001, f_affection@korea.kr

Received 5 March 2013 Revised 13 March 2013 Accepted 25 April 2013

Abstract

Objectives

This study was designed to investigate the clinical availability of quantitative electroencephalography (QEEG) as an auxiliary diagnostic tool in attention-deficit hyperactivity disorder (ADHD).

Methods

A total 95 participants completed examinations, which included Korean ADHD Rating Scale (K-ARS), Diagnostic Interview Schedule for Children Version IV-Korean Version (DISC-IV), and QEEG. From the result of the DISC-IV, we divided them into three groups, ADHD, ADHD NOS (not otherwise specified), and Normal control. The QEEG was analyzed by the ranges of Hz : delta (1-4 Hz), theta (4-8 Hz), alpha (8-12 Hz), beta (12-25 Hz), and high beta (25-30 Hz).

Results

ADHD NOS group showed significantly decreased delta activity (NOS<normal, p=0.003) and increased theta activity (NOS>normal, p=0.044) compared with normal control. ADHD group showed increased high beta activity (ADHD>NOS, p=0.043) compared with NOS group. The z-scores of relative power of theta were negatively correlated with the K-ARS at O1, O2 electrodes of ADHD group. On the other hand, the z-scores of relative power of high beta were negatively correlated with the K-ARS at F7, F8 electrodes of ADHD NOS group.

Conclusion

We confirmed QEEG abnormalities in ADHD patients, especially the difference between ADHD NOS and Normal control. Therefore, we expect to use QEEG as the valuable tool to diagnose ADHD accurately.

Keywords: ADHD, QEEG, DISC-IV, K-ARS

Figures and Tables

Fig. 1

The result of Pearson's correlation analysis between K-ARS and each z-score of relative power in ADHD group. ADHD : Attention-deficit hyperactivity disorder, K-ARS : Korean ADHD Rating Scale.

Fig. 2

The result of Pearson's correlation analysis between K-ARS and each z-score of relative power in ADHD NOS group. ADHD : Attention-deficit hyperactivity disorder, NOS : Not otherwise specified, K-ARS : Korean ADHD Rating Scale.

Table 1

Demographic characteristics of subjects (n=95)

Post hoc test : a : ADHD, NOS>Normal. ^*: p<0.05, ^**: p<0.01 by analysis of variance. ADHD : Attention-deficit hyperactivity disorder, NOS : Not otherwise specified, K-ARS : Korean ADHD Rating Scale

Table 2

Comparisons of five different band frequency among three groups

Post hoc test : a : Normal>NOS, b : NOS>Normal, c : ADHD>NOS. ^*: p<0.05, ^**: p<0.01 by analysis of variance. ADHD : Attention-deficit hyperactivity disorder, NOS : Not otherwise specified

Notes

The authors have no financial conflicts of interest.

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