Abstract
Background and Objectives
Subjects and Methods
Results
Figures and Tables
Fig. 1
The benefit of statin on MACE before and after propensity matching in each of the 4 groups, which were divided according to the baseline level of high density lipoprotein cholesterol and triglyceride. Group A (HDL-C≥40 mg/dL and triglyceride<150 mg/dL; n=11819), group B (HDL-C≥40 mg/dL and triglyceride≥150 mg/dL; n=3329), group C (HDL-C<40 mg/dL and triglyceride<150 mg/dL; n=6062) and group D (HDL-C<40 mg/dL and triglyceride≥150 mg/dL; n=3443). MACE: major adverse cardiac event, HDL-C: high density lipoprotein cholesterol, HR: hazard ratio, CI: confidence interval.
![kcj-46-324-g001](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-g001.jpg)
Fig. 2
The benefit of statin on the secondary end point in each of the 4 groups. Group A (HDL-C≥40 mg/dL and triglyceride<150 mg/dL; n=11819), group B (HDL-C≥ 40 mg/dL and triglyceride≥150 mg/dL; n=3329), group C (HDL-C<40 mg/dL and triglyceride<150 mg/dL; n=6062), and group D (HDL-C<40 mg/dL and triglyceride≥150 mg/dL; n=3443). HDL-C: high density lipoprotein cholesterol, CD: cardiac death, MI: myocardial infarction, TVR: target vessel revascularization, TLR: target lesion revascularization, HR: hazard ratio, CI: confidence interval.
![kcj-46-324-g002](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-g002.jpg)
Fig. 3
Comparison of changes of the levels of triglyceride (A), HDL-C (B), LDL-C (C), and hs-CRP (D) after statin therapy between group A and group D. HDL-C: high density lipoprotein cholesterol, LDL-C: low density lipoprotein cholesterol, hs-CRP: high sensitivity C-reactive protein.
![kcj-46-324-g003](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-g003.jpg)
Table 1
Comparison of clinical baseline characteristics after propensity score matching in group A (HDL-C≥40 mg/dL and TG<150 mg/dL) and group B (HDL-C≥40 mg/dL and TG≥150 mg/dL)
![kcj-46-324-i001](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-i001.jpg)
Values are n (%) or mean±standard deviation. HDL-C: high density lipoprotein cholesterol, TG: triglyceride, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, HR: hazard ratio, IHD Hx.: ischemic heart disease history, HTN Hx.: hypertension history, DM: diabetes mellitus, HL Hx.: hyperlipidemia history, MI: myocardial infarction, STEMI: ST-segment elevation myocardial infarction, NSTEMI: non-ST segment elevation myocardial infarction, PCI: percutaneous coronary intervention, LVEF: left ventricular ejection fraction, CK-MB: creatine kinase-MB, LDL-C: low density lipoprotein cholesterol, Hs CRP: high sensitivity C-reactive protein, NT pro BNP: N-terminal pro-brain natriuretic peptide, HbA1c: hemoglobin A1C, LMWH: low molecular weight heparin, RAAS: rennin angiotensin aldosterone system
Table 2
Comparison of clinical baseline characteristics after propensity score matching in group C (HDL-C<40 mg/dL and TG<150 mg/dL) and group D (HDL-C<40 mg/dL and TG≥150 mg/dL)
![kcj-46-324-i002](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-i002.jpg)
Values are n (%) or mean±standard deviation. HDL-C: high density lipoprotein cholesterol, TG: triglyceride, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, HR: hazard ratio, IHD Hx.: ischemic heart disease history, HTN: hypertension, DM: diabetes mellitus, HL: hyperlipidemia, MI: myocardial infarction, STEMI: ST-segment elevation myocardial infarction, NSTEMI: non-ST segment elevation myocardial infarction, PCI: percutaneous coronary intervention, LVEF: left ventricular ejection fraction, CK-MB: creatine kinase-MB, LDL-C: low density lipoprotein cholesterol, Hs CRP: high sensitivity C-reactive protein, NT pro BNP: N-terminal pro-brain natriuretic peptide, HbA1c: hemoglobin A1C, LMWH: low molecular weight heparin, RAAS: rennin angiotensin aldosterone system
Table 3
Comparison of coronary angiographic and procedural characteristics after propensity score matching in group A (HDL-C≥40 mg/dL and TG<150 mg/dL) and group B (HDL-C≥40 mg/dL and TG≥150 mg/dL)
![kcj-46-324-i003](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-i003.jpg)
Values are n (%) or mean±standard deviation. HDL-C: high density lipoprotein cholesterol, TG: triglyceride, TIMI: thromboysis in myocardial infarction, LM: left main, LAD: left anterior descending artery, LCX: left circumflex artery, RCA: right coronary artery, BMS: bare metal stent, DES: drug-eluting stent
Table 4
Comparison of angiographic and procedural characteristics after propensity score matching in group C (HDL-C<40 mg/dL and TG<150 mg/dL) and group D (HDL-C<40 mg/dL and TG≥150 mg/dL)
![kcj-46-324-i004](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-i004.jpg)
Table 5
The impact of statin therapy on primary end point after propensity score matching
![kcj-46-324-i005](/upload/SynapseData/ArticleImage/0054kcj/kcj-46-324-i005.jpg)
The covariates in this multivariate analysis were age over 65 years, hypertension, diabetes mellitus, left ventricular ejection fraction, Killip classification, post-TIMI flow, and the use of aspirin, clopidogrel, beta-blocker, and renin-angiotensin system blocker. TIMI: thrombolysis in myocardial infaction, HR: hazard ratio, CI: confidence interval