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Kim, Suh, Kim, Han, Jung, and Ryu: Clinical Utility and Accuracy of Coaguchek® XS, a Reliable Alternative to Laboratory International Normalized Ratio Monitoring in Korean Patients With Atrial Fibrillation
Original Article
Korean Circulation Journal

Korean Circulation Journal 2009; 39(2): 71-74.

Published online: 26 February 2009

DOI: https://doi.org/10.4070/kcj.2009.39.2.71

Clinical Utility and Accuracy of Coaguchek® XS, a Reliable Alternative to Laboratory International Normalized Ratio Monitoring in Korean Patients With Atrial Fibrillation

Sung Hea Kim, MD, Soon Yong Suh, MD, Hyun-Joong Kim, MD, Seong Woo Han, MD, Sang Man Jung, MD, Kyu Hyung Ryu, MD

Department of Cardiology, Konkuk University School of Medicine, Seoul, Korea.

Correspondence: Kyu Hyung Ryu, MD, Department of Cardiology, Konkuk University School of Medicine, 4-12 Hwayang-dong, Gwangjin-gu, Seoul 143-729, Korea. Tel: 82-2-2049-6355, Fax: 82-2-2049-6355, khryu@kuh.ac.kr

Received 11 September 2008       Accepted 17 October 2008

Copyright © 2009 The Korean Society of Cardiology

Abstract

Background and Objectives

To evaluate the accuracy and the clinical utility of the Coaguchek® XS, a portable point-of-care coagulometer, compared to standard laboratory methods in Korean patients.

Subjects and Methods

We included 107 patients with atrial fibrillation on long-term oral warfarin therapy. The prothrombin time as expressed by the international normalized ratio (INR) was measured by the portable Coaguchek® XS system as well as standard laboratory methods. Agreement between the two methods was defined as a difference of less than 0.3 between the INR values.

Results

The INR determined by the portable Coaguchek® XS had excellent correlation with the values obtained by standard methods (r=0.984, p<0.01). The INR determined by the portable Coaguchek® XS tended to be high among the high INR group values (standard INR>3.0). There was a 91.6% agreement between the two methods. Only nine cases (8.4%) had a difference of more than 0.3; this was mainly noted in the high INR group.

Conclusion

The portable self-testing of the INR by the Coaguchek® XS might be a reliable alternative to hospital based laboratory testing in Korean patients.

Keywords: Atrial fibrillation, Prothrombin time

Figures and Tables

Fig. 1
The correlation between INRs by Coaguchek® XS and standard laboratory test (r=0.984, p<0.01). INR: international normalized ratio.
kcj-39-71-g001
Fig. 2
Bland-Altman Plot of the difference between INRs obtained by the Coaguchek® XS and standard laboratory testing. INR: international normalized ratio.
kcj-39-71-g002
Table 1
The difference and the agreement between the two methods according to the INR level
kcj-39-71-i001

ΔINR: Coagucheck INR-standard INR, INR: international normalized ratio

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