Acute myocardial infarction is generally caused by the rupture or erosion of an atheromatous plaque and thrombosis. Acute myocardial infarction associated with a myocardial bridge or slow coronary flow is rare. We experienced a case of acute myocardial infarction, caused by a coronary thrombus in association with a myocardial bridge and slow coronary flow. A 33-year-old man presented with the sudden onset of chest pain. A diagnostic coronary angiography revealed an intraluminal contrast-filling defect, proximal to the myocardial bridge in the left anterior descending artery, with TIMI-2 flow. After an intracoronary injection of 150,000 units of urokinase and an intravenous injection of abciximab, the patient's chest pain subsided, with the follow-up coronary angiography showing the disappearance of the coronary thrombus.