Aggressively Progressed MRSA Sepsis Accompanied by Endophthalmitis and Endocarditis in Preterm Infant

Jeong Min Lee; Ji Hye Hwang; Dae Yong Yi; Na Mi Lee; Sin Weon Yun; Soo Ahn Chae; Eung Sang Choi; Jee Taek Kim; Hyery Kim; In Seok Lim

doi:10.14734/kjp.2015.26.4.369

Journal List > Korean J Perinatol > v.26(4) > 1013779

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Lee, Hwang, Yi, Lee, Yun, Chae, Choi, Kim, Kim, and Lim: Aggressively Progressed MRSA Sepsis Accompanied by Endophthalmitis and Endocarditis in Preterm Infant

Case Report

Korean J Perinatol 2015;26(4):369-372.

Published online: 20 December 2015

DOI: https://doi.org/10.14734/kjp.2015.26.4.369

Aggressively Progressed MRSA Sepsis Accompanied by Endophthalmitis and Endocarditis in Preterm Infant

Jeong Min Lee, M.D.¹, Ji Hye Hwang, M.D.¹, Dae Yong Yi, M.D., Ph.D.¹, Na Mi Lee^1,, Sin Weon Yun, M.D., Ph.D.¹, Soo Ahn Chae, M.D., Ph.D.¹, Eung Sang Choi, M.D., Ph.D.¹, Jee Taek Kim, M.D., Ph.D.², Hyery Kim, M.D., Ph.D.¹, In Seok Lim, M.D., Ph.D.¹

¹Department of Pediatrics, Chung-Ang University College of Medicine, Seoul, Korea

²Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Korea

Correspondence to: Na Mi Lee, M.D., Ph.D. Department of Pediatrics, Chung-Ang University Hospital, 102, Heukseok-ro, Dongjak-gu, Seoul, 06973, Korea Tel: +82-2-6299-3181, Fax: +82-2-6264-2167 E-mail: piena81@hotmail.com

Received 27 September 2015 Revised 21 October 2015 Accepted 27 October 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a critical source of infections in neonatal intensive care units. Early diagnosis and treatment are important due to the significant morbidity of MRSA infection. MRSA sepsis can be disseminated despite antibiotics, therefore the extent of the infection should be evaluated. Common complications of MRSA sepsis include infective endocarditis, pneumonia, osteomyelitis, meningitis, septic shock.Urgent evaluation of other possible suppurative complications in neoate are necessary. Therefore echocardiogram, chest X-ray, ophthalmic examination, brain sonography and spinal tapping are needed. In this study, we present a case of MRSA sepsis in a preterm infant, accompanied by endophthalmitis and endocarditis in spite of the early diagnosis and treatment.

Keywords: Methicillin-resistant Staphylococcus aureus, Sepsis, Endophthalmitis, Endocarditis

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Fig. 1.

Clinical photographs of both eyes with endophthalmitis.

Fig. 2.

Echocardiography showing a large vegetation on tricuspid valve.

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