Journal List > Korean J Perinatol > v.26(2) > 1013748

Kang: A Case of Maternal Herpes Simplex Virus Type 2 Encephalitis without Genital Skin Lesion

Abstract

Herpes simplex encephalitis is the most common form of encephalitis, but herpes simplex virus type 2 (HSV-2) encephalitis is very rare during pregnancy. In immunocompetent patients, HSV-2 encephalitis is usually mild. With early diagnosis and prompt initiation of antiviral treatment, as well as enhanced neurocritical care, a favorable outcome can be expected in both mother and neonate. We report a rare case of maternal HSV-2 encephalitis diagnosed by polymerase chain reaction following appendectomy. The woman had no symptomatic genital lesion, and the infant was not infected.

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Fig. 1.
Section of the appendix shows a few neutrophils in muscularis propria (H&E, ×200).
kjp-26-139f1.tif
Fig. 2.
Brain MRI scans of a patient with HSV-2 encephalitis during pregnancy. It was within normal limit.
kjp-26-139f2.tif
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