Paroxysmal Supraventricular Tachycardia at 1-Month Age and Transient Thyroid Dysfunction in a Preterm Baby Treated for Fetal Tachycardia with Amiodarone

Seung Woo Nam; Sun Young Ko; Yeon Kyung Lee; So Young Yoon; Sung Won Park; Son Soon Shin

doi:10.14734/kjp.2014.25.3.189

Journal List > Korean J Perinatol > v.25(3) > 1013717

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Nam, Ko, Lee, Yoon, Park, and Shin: Paroxysmal Supraventricular Tachycardia at 1-Month Age and Transient Thyroid Dysfunction in a Preterm Baby Treated for Fetal Tachycardia with Amiodarone

Original Article

Korean J Perinatol 2014;25(3):189-194.

Published online: 21 September 2014

DOI: https://doi.org/10.14734/kjp.2014.25.3.189

Paroxysmal Supraventricular Tachycardia at 1-Month Age and Transient Thyroid Dysfunction in a Preterm Baby Treated for Fetal Tachycardia with Amiodarone

Seung Woo Nam, M.D., Sun Young Ko, M.D., Yeon Kyung Lee, M.D., So Young Yoon, M.D., Sung Won Park, M.D., Son Soon Shin, M.D.

Department of Pediatrics, Cheil General Hospital and Women’s Healthcare Center, Kwandong University, College of Medicine, Seoul, Korea

Received 2 May 201412 June 2014 Accepted 12 July 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Fetal tachycardia is mostly benign, but sometimes results in serious consequences such as fetal hydrops and fetal death. To decrease cardiovascular burden, fetuses could be treated with transplacental administration of antiarrhythmic drugs such as digoxin, amiodarone. Although amiodarone has been proven to be effective against fetal tachycardia, it is also known to cause transient neonatal thyroid dysfunction and neurodevelopmental delay in some patients. Nonetheless, there has been only few postnatal follow-up studies with the patients who were diagnosed and treated for fetal tachycardia although majority of postnatal arrhythmias occurred within the first 48 hours of life in a recent report. We report a newborn with transient thyroid dysfunction and late-onset supraventricular tachycardia at 1 month age, who had fetal tachycardia treated with amiodarone at the 25th week of pregnancy.

Keywords: Tachycardia, Amiodarone, Hypothyroidism, Newborn

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Fig. 1.

Twelve leads from electrocardiogram recorded at birth with normal sinus rhythm.

Fig. 2.

Lead II from electrocardiogram recorded (A) at 1 month age with supraventricular tachycardia, and (B) after administration of adenosine, showing termination of tachycardia.

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