Journal List > J Korean Orthop Assoc > v.52(4) > 1013532

Lee, Hwang, Jeong, Oh, and Kim: Risk Factors of Cut-Out in Treatment of Femoral Intertrochanteric Fractures by Proximal Femur Nail

Abstract

Purpose

The purpose of this study is to evaluate the risk factors for the occurrence of cut-out of proximal femoral nail by a lag screw as the treatment for intertrochanteric fractures.

Materials and Methods

A total of 151 patients (76 males and 75 females; mean age, 73.7±12.1 years), who were diagnosed with intertrochanteric fracture at Gyeongsang National University Hospital between January 2011 and March 2016, with a follow-up of at least for 6 months were included in this retrospective study. Various risk factors, such as demographic data, osteoporosis, collodiaphyseal angle (CDA) (≤130˚ or >130˚), tip-apex distance (TAD) (≤25 mm or >25 mm), and the position of lag screw in the femur head (quadrant) related to the occurrence of cut-out were taken into consideration. The strength of association for each factor was determined through the calculation of the odds ratio (OR), within the 95% confidence interval (CI). First, we performed univariate logistic regression analyses for all variables; then, we performed a multivariate logistic regression analysis, using only the significant variables that had resulted from the univariate analysis.

Results

Among the 151 cases, the occurrence of cut-out was observed in 14 cases (9.3%). In a univariate analysis, the fracture patterns based on the AO/OTA classification (p=0.045), CDA (p<0.001) and the position of lag screw in the femur head (quadrant) (p=0.001) showed a significant association with the occurrence of the cut-out. However, TAD was not significantly associated with the cut-out (p=0.886). Various factors, which were significant in univariate analyses, were included in multivariate analyses. In multivariate analyses, CDA (OR, 12.291; 95% CI, 2.559-59.034; p=0.002), and quadrant (OR, 7.194; 95% CI, 1.712-30.303; p=0.007) were significantly associated with the cut-out.

Conclusion

Valgus reduction and proper position of lag screw were critical for the prevention of occurrence of cut-out when treating intertrochanteric fracture using proximal femur nail.

REFERENCES

1. Hagino H, Yamamoto K, Ohshiro H, Nakamura T, Kishimoto H, Nose T. Changing incidence of hip, distal radius, and proximal humerus fractures in Tottori Prefecture, Japan. Bone. 1999; 24:265–70.
crossref
2. Richmond J, Aharonoff GB, Zuckerman JD, Koval KJ. Mortality risk after hip fracture. J Orthop Trauma. 2003; 17:53–6.
crossref
3. Koval KJ, Aharonoff GB, Rokito AS, Lyon T, Zuckerman JD. Patients with femoral neck and intertrochanteric fractures. Are they the same? Clin Orthop Relat Res. 1996; 330:166–72.
crossref
4. Barton TM, Gleeson R, Topliss C, Greenwood R, Harries WJ, Chesser TJ. A comparison of the long gamma nail with the sliding hip screw for the treatment of AO/OTA 31-A2 fractures of the proximal part of the femur: a prospective randomized trial. J Bone Joint Surg Am. 2010; 92:792–8.
5. Schipper IB, Steyerberg EW, Castelein RM. . Treatment of unstable trochanteric fractures. Randomised comparison of the gamma nail and the proximal femoral nail. J Bone Joint Surg Br. 2004; 86:86–94.
6. Haidukewych GJ, Israel TA, Berry DJ. Reverse obliquity fractures of the intertrochanteric region of the femur. J Bone Joint Surg Am. 2001; 83:643–50.
crossref
7. Sadowski C, Lübbeke A, Saudan M, Riand N, Stern R, Hoff-meyer P. Treatment of reverse oblique and transverse intertrochanteric fractures with use of an intramedullary nail or a 95 degrees screw-plate: a prospective, randomized study. J Bone Joint Surg Am. 2002; 84:372–81.
8. Parker MJ, Handoll HH. Gamma and other cephalocondylic intramedullary nails versus extramedullary implants for extracapsular hip fractures in adults. Cochrane Database Syst Rev. 2010; 9:CD000093.
crossref
9. Riina J, Tornetta P 3rd, Ritter C, Geller J. Neurologic and vascular structures at risk during anterior-posterior locking of retrograde femoral nails. J Orthop Trauma. 1998; 12:379–81.
crossref
10. Mavrogenis AF, Panagopoulos GN, Megaloikonomos PD. . Complications after hip nailing for fractures. Orthopedics. 2016; 39:e108–16.
crossref
11. Lorich DG, Geller DS, Nielson JH. Osteoporotic pertrochanteric hip fractures: management and current controversies. Instr Course Lect. 2004; 53:441–54.
12. Kim WY, Han CH, Park JI, Kim JY. Failure of intertrochanteric fracture fixation with a dynamic hip screw in relation to pre-operative fracture stability and osteoporosis. Int Orthop. 2001; 25:360–2.
crossref
13. Baumgaertner MR, Curtin SL, Lindskog DM, Keggi JM. The value of the tip-apex distance in predicting failure of fixation of peritrochanteric fractures of the hip. J Bone Joint Surg Am. 1995; 77:1058–64.
crossref
14. Wu CC, Shih CH, Chen WJ, Tai CL. Treatment of cutout of a lag screw of a dynamic hip screw in an intertrochanteric fracture. Arch Orthop Trauma Surg. 1998; 117:193–6.
crossref
15. Cleveland M, Bosworth DM, Thompson FR, Wilson HJ Jr, Ishizuka T. A ten-year analysis of intertrochanteric fractures of the femur. J Bone Joint Surg Am. 1959; 41:1399–408.
crossref
16. Yu J, Zhang C, Li L. . Internal fixation treatments for intertrochanteric fracture: a systematic review and meta-analysis of randomized evidence. Sci Rep. 2015; 5:18195.
crossref
17. Shen J, Hu C, Yu S, Huang K, Xie Z. A meta-analysis of percutenous compression plate versus intramedullary nail for treatment of intertrochanteric HIP fractures. Int J Surg. 2016; 29:151–8.
crossref
18. Long H, Lin Z, Lu B. . Percutaneous compression plate versus dynamic hip screw for treatment of intertrochanteric hip fractures: a overview of systematic reviews and update meta-analysis of randomized controlled trials. Int J Surg. 2016; 33:1–7.
crossref
19. Pajarinen J, Lindahl J, Savolainen V, Michelsson O, Hirven-salo E. Femoral shaft medialisation and neck-shaft angle in unstable pertrochanteric femoral fractures. Int Orthop. 2004; 28:347–53.
crossref
20. Hsueh KK, Fang CK, Chen CM, Su YP, Wu HF, Chiu FY. Risk factors in cutout of sliding hip screw in intertrochanteric fractures: an evaluation of 937 patients. Int Orthop. 2010; 34:1273–6.
crossref
21. Parker MJ. Valgus reduction of trochanteric fractures. Injury. 1993; 24:313–6.
crossref
22. Andruszkow H, Frink M, Frömke C, et al. Tip apex distance, hip screw placement, and neck shaft angle as potential risk factors for cut-out failure of hip screws after surgical treatment of intertrochanteric fractures. Int Orthop. 2012; 36:2347–54.
crossref
23. Kuzyk PR, Zdero R, Shah S, Olsen M, Waddell JP, Schemitsch EH. Femoral head lag screw position for cephalomedul-lary nails: a biomechanical analysis. J Orthop Trauma. 2012; 26:414–21.
24. Davis TR, Sher JL, Horsman A, Simpson M, Porter BB, Checketts RG. Intertrochanteric femoral fractures. Mechanical failure after internal fixation. J Bone Joint Surg Br. 1990; 72:26–31.
crossref
25. Den Hartog BD, Bartal E, Cooke F. Treatment of the unstable intertrochanteric fracture. Effect of the placement of the screw, its angle of insertion, and osteotomy. J Bone Joint Surg Am. 1991; 73:726–33.
crossref
26. Geller JA, Saifi C, Morrison TA, Macaulay W. Tip-apex distance of intramedullary devices as a predictor of cut-out failure in the treatment of peritrochanteric elderly hip fractures. Int Orthop. 2010; 34:719–22.
crossref
27. Herman A, Landau Y, Gutman G, Ougortsin V, Chechick A, Shazar N. Radiological evaluation of intertrochanteric fracture fixation by the proximal femoral nail. Injury. 2012; 43:856–63.
crossref
28. Mingo-Robinet J, Torres-Torres M, Martínez-Cervell C, et al. Comparative study of the second and third generation of gamma nail for trochanteric fractures: review of 218 cases. J Orthop Trauma. 2015; 29:e85–90.
29. Kraus M, Krischak G, Wiedmann K. . Clinical evaluation of PFNA® and relationship between the tip-apex distance and mechanical failure. Unfallchirurg. 2011; 114:470–8.
30. Kane P, Vopat B, Heard W. . Is tip apex distance as important as we think? A biomechanical study examining optimal lag screw placement. Clin Orthop Relat Res. 2014; 472:2492–8.
crossref

Figure 1
Determination of the quadrant on anteroposterior view (A) and lateral view (B).
jkoa-52-319f1.tif
Table 1
Demographic Data of the Patients in Each Group
Variable Cut-out (+) (n=14) Cut-out (-) (n=137) p-value
Age (yr) 73.0±10.2 73.8±12.4 0.813
Sex (male:female e) 7:7 69:68 0.979
Weight (kg) 57.9±14.1 55.2±9.7 0.357
Height (cm) 160.3±6.8 160.5±9.7 0.935
BMI (kg/m2) 22.6±5.4 21.4±3.3 0.459
Smoking 3 36 0.693
DM 6 30 0.080
Osteoporosis 10 77 0.272
TAD (mm) 0.886
≤25 8 81
>25 6 56
Mean TAD (mm) 29.7±9.7 27.5±6.7 0.276
CDA (°) <0.001
≤130 5 5
>130 9 132
Quadrant 0.001
Acceptable 9 127
Unacceptable 5 10
Nail length 0.569
Short 10 107
Long 4 30
Nail type 0.174
PFNA 10 62
Gamma nail 3 54
InterTAN nail 1 21

Values are presented as mean±standard deviation or number only. BMI, body mass index; DM, diabetes mellitus; TAD, tip-apex distance; CDA, collodiaphyseal angle; PFNA, proximal femur nail antirotation.

Table 2
Distribution of Fractures according to AO the Classification*
AO classification Cut-out (+) Cut-out (-) Total
31 A1.1 0 (0.0) 35 (23.2) 35 (23.2)
31 A1.2 2 (1.3) 22 (14.6) 24 (15.9)
31 A1.3 2 (1.3) 13 (8.6) 15 (9.9)
31 A2.1 3 (2.0) 31 (20.5) 34 (22.5)
31 A2.2 1 (0.7) 14 (9.3) 15 (9.9)
31 A2.3 4 (2.6) 6 (4.0) 10 (6.6)
31 A3.1 1 (0.7) 7 (4.6) 8 (5.3)
31 A3.2 1 (0.7) 5 (3.3) 6 (4.0)
31 A3.3 0 (0.0) 4 (2.6) 4 (2.6)
Total 14 (9.3) 137 (90.7) 151 (100.0)

Values are presented as number (%).

* p=0.040.

Table 3
Analysis of Postoperative Neck-Shaft Angle Difference to the Un-Injured Side
Difference to contralateral side Total Cut-out frequency
<-5° (varus) 8 5 (62.5)
-5°–0° 34 4 (11.8)
0°–5° 53 3 (5.7)
5°–10° 40 1 (2.5)
>10° (valgus) 16 1 (6.3)

Values are presented as number only or number (%).

Table 4
The Statistical Outcomes of the Present Study
Variable Univariate logistic regression test Multivariate logistic regression test
p-value OR (95% CI) p-value OR (95% CI)
Age 0.812 0.995 (0.952–1.040)
Sex 0.979 1.015 (0.338–3.048)
BMI 0.253 1.091 (0.939–1.267)
DM 0.089 0.374 (0.120–1.161)
Smoking 0.694 1.307 (0.345–4.952)
Osteoporosis 0.272 1.948 (0.582–6.517)
AO/OTA type 0.045 1.275 (1.005–1.617) 0.295 1.171 (0.872–1.572)
TAD (≤25 or >25 mm ) 0.886 1.085 (0.357–3.298)
CDA <0.001 14.705 (3.571–58.824) 0.002 12.291 (2.559–59.034)
Quadrant 0.001 7.056 (1.984–25.090) 0.007 7.194 (1.712–30.303)
Nail length 0.569 1.427 (0.418–4.872)
Nail type 0.098 0.446 (0.172–1.160)

OR, odds ratio; CI, confidence interval; BMI, body mass index; DM, diabetes mellitus; TAD, tip-apex distance; CDA, collodiaphyseal angle.

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