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Jeong, Hong, Park, Seo, Oh, Yoon, Kyung, and Kim: Quality of Life in Patients with Osteochondromatosis
Original Article

Journal of the Korean Orthopaedic Association 2016; 51(2): 139-144.

Published online: 22 April 2016

DOI: https://doi.org/10.4055/jkoa.2016.51.2.139

Quality of Life in Patients with Osteochondromatosis

Won-Ju Jeong, M.D., Nam-Soo Hong, M.D.*, Il-Hyung Park, M.D., Il Seo, M.D., Chang-Wug Oh, M.D., Jong Pil Yoon, M.D., Hee-Soo Kyung, M.D., Ha-Jeong Kim, M.D.†

Department of Orthopedic Surgery, Kyungpook National University School of Medicine, Daegu, Korea.

*Department of Preventive Medicine, Kyungpook National University School of Medicine, Daegu, Korea.

†Department of Physiology, Kyungpook National University School of Medicine, Daegu, Korea.

Correspondence to: Nam-Soo Hong, M.D. Department of Preventive Medicine, Kyungpook National University School of Medicine, 680 Gukchaebosang-ro, Jung-gu, Daegu 41944, Korea. TEL: +82-53-420-4864, FAX: +82-53-422-5628, kusmac25@knu.ac.kr

Received 7 May 2015       Revised 5 September 2015       Accepted 14 October 2015

Copyright © 2016 by The Korean Orthopaedic Association

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study is to help predict the prognosis of multiple osteochondromatosis patients with the investigation of social function, pain, physical function and quality of life of patients.

Materials and Methods

Forty-five cases were diagnosed as multiple osteochondromatosis from March 1993 to June 2014. We performed a survey on pain, daily life, school or work life assessment of research and development-36. Forty-five people who responded to the survey completely were enrolled. Variable factors, including physical functioning, role limitations due to physical health, role limitations due to emotional problems, energy/fatigue, emotional well-being, social functioning, pain, and general health state were considered as elements related to quality of life. In addition, we investigated significant factors for multiple osteochondromatosis patients, and analyzed the survey by scoring. Related factors included age (over 18 years and under 18 years), gender, body mass index, operation, joint deformity, recurrence of disease, family history, the number of involved joints and the location of tumor. Statistical analyses were performed using SAS ver. 9.3 (SAS Inc., Cary, NC, USA). p-values of <0.05 were deemed statistically significant.

Results

Patients with a family history of multiple osteochondromatosis showed a significantly decreased result of assessment, physical function, vitality of life, social activities, and health state. In addition, there was a tendency of a poor influence in pain, emotional wellbeing, and general health.

Conclusion

The results suggest that family history is a significant factor influencing and predicting the quality of life. In other words, the developed patients in the household including patients with severe enough for the rest of the family to know have poor prognosis. Through this study multiple osteochondromatosis is a chronic disease having a profound impact on quality of life.

Keywords: multiple hereditary exostoses, quality of life, pain, family relations

Figures and Tables

Table 1

General and Clinical Characteristics of Participants

jkoa-51-139-i001

Values are presented as mean±standard deviation or number (%).

Table 2

Total RAND Score by General and Clinical Characteristics

jkoa-51-139-i002

Values are presented as mean±standard deviation. RAND, research and development.

Table 3

Factors Affecting RAND Score*

jkoa-51-139-i003

*Results of multiple regression analysis. RAND, research and development.

Notes

CONFLICTS OF INTEREST The authors have nothing to disclose.

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