The Clinical Characteristics, Treatments and Oncologic Outcomes of Chondroblastoma: Comparison with Giant Cell Tumor

Duk-Seop Shin; Chi-Bum Choi; Jae-Woo Park; Ho-Dong Na

doi:10.4055/jkoa.2016.51.2.133

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Shin, Choi, Park, and Na: The Clinical Characteristics, Treatments and Oncologic Outcomes of Chondroblastoma: Comparison with Giant Cell Tumor

Original Article

Journal of the Korean Orthopaedic Association 2016; 51(2): 133-138.

Published online: 22 April 2016

DOI: https://doi.org/10.4055/jkoa.2016.51.2.133

The Clinical Characteristics, Treatments and Oncologic Outcomes of Chondroblastoma: Comparison with Giant Cell Tumor

Duk-Seop Shin, M.D., Chi-Bum Choi, M.D., Jae-Woo Park, M.D., Ho-Dong Na, M.D.

Department of Orthopedic Surgery, Yeungnam University Medical Center, Daegu, Korea.

Correspondence to: Duk-Seop Shin, M.D. Department of Orthopedic Surgery, Yeungnam University Medical Center, 170 Hyeonchung-ro, Nam-gu, Daegu 42415, Korea. TEL: +82-53-620-3640, FAX: +82-53-628-4020, dukseop@gmaill.com

Received 11 May 2015 Revised 31 July 2015 Accepted 21 September 2015

(open-access):

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of the study was to compare clinical, oncological outcomes between chondroblastoma and giant cell tumor.

Materials and Methods

This retrospective study reviewed 25 patients with histologically confirmed chondroblastoma of bone between 1998 and 2012. During the same period, 42 patients diagnosed as a giant cell tumor were also reviewed. We then analyzed clinical and oncological results of chondroblastoma compared with giant cell tumor. In chondroblastoma, 17 cases were male, and 8 cases were female, with a mean age of 20.6 years (range from 11 to 38 years). In giant cell tumor, 20 cases were male, and 22 cases were female, with a mean age of 39.26 years (from 17 to 75 years). All patients underwent surgical treatment that extended curettage with electrocauterization. After curettage, bony cavity was filled with autogenous bone, allogenic bone chip, bone cement, tricalcium phosphate, and so on. The results were compared in recurrence and metastatic rate. The minimum follow-up period was 1 year.

Results

In chondroblastoma, mean size was 2.18 cm (0.3 to 9.5 cm). Local recurrence and metastasis were absent. In giant cell tumors, mean size was 3.71 cm (0.3 to 11 cm). Local recurrence rate was 9.5% (4 of 42 cases) and there was one lung metastasis.

Conclusion

Chondroblastoma is less invasive with better prognosis than giant cell tumor. Treatment of chondroblastoma and giant cell tumor is surgery. Electrocauterization as an adjuvant therapy showed good results.

Keywords: chondroblastoma, giant cell tumors, prognosis

Figures and Tables

Figure 1

A 28-year-old female with humeral chondroblastoma. (A) Preoperative radiograph of the right proximal humerus. (B) Intraoperative radiograph and photo. After curettage and allochip bone graft, the opening site was covered with bone cement. (C) Follow-up radiograph 2 years after surgery.

Figure 2

A 62-year-old female with a distal femoral Giant cell tumor. (A) Preoperative radiograph of the right distal femur showing an osteolytic lesion. (B) Preoperative magnetic resonance image showing a heterogeneous mass with mild enhancement in the distal femur and in X-ray, showing a skin stapler after making a parapatella incision at the local medical center. (C) Intraoperative gross photo, after extended curettage and electrocauterization, the cavity was filled with allochip bone and the opening site was covered with bone cement. (D) Postoperative radiograph and the patient underwent a total knee arthroplasty 1 year later.

Table 1

Clinical and Oncologic Outcomes of Chondroblastoma: Comparison with Giant Cell Tumor

Values are presented as number only or median (range).

Notes

^{CONFLICTS OF INTEREST} The authors have nothing to disclose.

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