Journal List > J Korean Orthop Assoc > v.48(1) > 1013254

Cha, Kim, and Shin: Acute Tophaceous Gout of the Distal Interphalangeal Joint Misdiagnosed as Cellulitis

Abstract

In elderly patients, the first incidence of gout often affects the distal interphalangeal joint (DIP) and usually subsides without specific treatment after about 7 days. A 61-year-old male was presented to our clinic with a 10-day history of tenderness and swelling in his index DIP, which was initially diagnosed as cellulitis. After a skin incision was made to drain the lesion, typical tophaceous deposits were observed around the extensor apparatus, flexor tendons, and joint capsule. The tophi were meticulously removed in order to minimize the injury to its surrounding structures, after which the joint fluid was aspirated. There was no history of gout, laboratory findings suggesting tophaceous gout, or apparent predisposing factors in the patient's history. Pathology confirmed tophaceous deposits and negative birefringent crystals, and the patient has been managed on allopurinol for post-operative six months.

Figures and Tables

Figure 1
A simple radiograph of acute attack of gout in the distal interphalangeal joint at left index finger. There were no specific findings, except marked soft tissue swelling.
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Figure 2
(A) Appearance of the patient's dorsal left hand at presentation. (B) Surgical site after lateral skin incision with the typical appearance of a gouty tophus. The tophus was easily separated from the extensor apparatus, flexor tendon sheath, and capsule. Note the thin, transparent appearance of the capsule above the extensor apparatus. (C) Gross finding of tophaceous deposits.
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Figure 3
(A) Photomicrograph of a specimen demonstrating gouty tophus with synovial tissue (H&E stain, ×40). (B) Amorphous central material deposits (asterisks) surrounded by inflammatory cells (arrows) (H&E stain, ×200). (C) Needle-shaped urate crystal from distal interphalangeal joint fluid showing negative birefringence under compensated polarized light microscopy.
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Table 1
Laboratory Values at Admission
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BUN, blood urea nitrogen.

Table 2
Laboratory Values at Postoperative 1 Day
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