Journal List > J Korean Orthop Assoc > v.45(1) > 1013048

Hwang, Lim, Kim, Kim, Moon, Lee, and Cho: Acroosteolysis of Scleroderma Associated with a Felon

Abstract

The Scleroderma is a chronic inflammatory disease of the connective tissue with involvement of the skin and other organs. It can be a manifestation of various disorders and occasionally acroosteolysis in the phalanges. Acroosteolysis is characterized by bone resorption or destruction in the phalanges, while the base is preserved. The pathogenesis of acroosteolysis in patients with scleroderma is a blood-flow disorder that is mainly associated with an abnormal accumulation of collagen in all tissues, microangiopathy and infections in the phalanges. The phalanges in patients with scleroderma are prone to continuous infections as a felon or skin ulcers due to atrophy of the subcutaneous tissue, dry and sclerotic skin, or a disorder of the immune system. We experienced a patient who had acroosteolysis with scleroderma of the phalanges, and this was associated with a felon. We report on this case along with a brief review of the literature.

Figures and Tables

Figure 1
Photograph shows shortening and sclerotic thickening of fingers with a felon.
jkoa-45-88-g001
Figure 2
Radiograph of both hands shows acroosteolysis of distal phalanges excluding second and fifth finger in left hand.
jkoa-45-88-g002
Figure 3
In fingertip, there was severe inflammatory and degenerative pulp with neutrophil infiltration (white arrow) and abnormal accumulative collagen (black arrow) (H-E stain, ×200).
jkoa-45-88-g003

References

1. Gama C, Meira JB. Occupational acroosteolysis. J Bone Joint Surg Am. 1978. 60:89–90.
crossref
2. Todd G, Saxe N. Idiopathic osteolysis. Arch Dermatol. 1994. 130:759–762.
3. Destouet JM, Murphy WA. Acquired acroosteolysis and acronecrosis. Arthritis Rhuem. 1983. 26:1150–1154.
crossref
4. Meszaros WT. The regional manifestations of scleroderma. Radiology. 1958. 70:313–325.
crossref
5. Hong YS, Yang HI, Park SH, Lee SH, Cho CS, Kim HY. A case of Sjogren syndrome associated with acroosteolysis. J Korean Rheum Assoc. 1996. 3:92–96.
6. Clark DC. Common acute hand infections. Am Fam Physician. 2003. 68:2167–2176.
7. D'Angelo WA, Fries JF, Masi AT, Shulman LE. Pathologic observations in systemic sclerosis (scleroderma). A study of fifty-eight autopsy cases and fifty-eight matched controls. Am J Med. 1969. 46:428–440.
8. Kreig T, Meurer M. Systemic sclerosis. Clinical and pathophysiologic aspects. J Am Acad Dermato. 1988. 18:457–481.
9. Subcommittee for scleroderma criteria of the American Rhematism Association Diagnostic and Therapeutic Criteria Committee. Preliminary criteria for the classification of systemic sclerosis (scleroderma). Arthritis Rheum. 1980. 23:581–590.
10. Avouac J, Guerini H, Wipff J, et al. Radiological hand involvement in systemic sclerosis. Ann Rheum Dis. 2006. 65:1088–1092.
crossref
TOOLS
Similar articles